I built an MVP that's been running in production for two customers entirely in Laravel and Semantic UI (CSS). When the need to a better UI was a concern, I added bits of client side Vue.
Now I'm rewriting my front end entirely in Svelte(Kit) and Tailwind, and keeping the Laravel backend for now. I will experiment with more lightweight PHP backends and Rust in this rewrite just to see how good (or bad) things can get.