It's possible if you do a wipe and do a fresh install. You essentially boot into the Sequoia installer. I'm also looking at possibly picking up a M5 MBP and was the first things I looked into.
The Shield Pro is perfect for me and I have no reason to upgrade. Have mine downgraded and de-bloated using this guide [0] running a custom launcher. Like you said being Android and more open helps a lot.
The install script is still there, you don't have to use the ISO [0]. I prefer to do my own btrfs subvolumes, partitioning, tweaks, etc and just run the script after a base install. Uninstalling anything is a matter of seconds from the provided menus.
Obligatory list of workflow engines and libraries because it's such a common need that a lot have rolled their own. [1]
[0] https://docs.dbos.dev/python/tutorials/database-connection
[1] https://github.com/meirwah/awesome-workflow-engines