You are probably right it was timed deliberately this way, this is why the Iranians also
didn't rush it ...
> Iran waited until the clock passed midnight local time to finalize the agreement, because it did not want the momentous occasion to coincide with President Trump’s birthday on Sunday, according to two Iranian officials who could not be identified because of the matter’s sensitivity. The seven-and-half-hour time difference allowed both Tehran and Washington to claim their preferred version of when the deal was finalized. President Trump had said it would be on Sunday, and Iran had said it would be on a later day.[0]
For context the Cell paper published several weeks before [0][1] provides a more bird's eye view (multi-omics etc.) the Nature paper here is very hands on providing x-ray crystal structures etc.
It is unfortunate that at some point in midst of numerous renaming itself after a brief stint in mass media around 2014 the programming on both side was so successful that the latin string of "isis" to this day is basically reduced in many westerners minds as a pavlovian reflex to this meaning, ironic because most arabs in egypt and elsewhere lack the association
so kudos to the article/institute, leaving as it is
great band btw
> The name ISIS is not an acronym: it refers to the Ancient Egyptian goddess and the local name for the River Thames. The name was selected for the official opening of the facility in 1985, prior to this it was known as the SNS, or Spallation Neutron Source. The name was considered appropriate as Isis was a goddess who could restore life to the dead, and ISIS made use of equipment previously constructed for the Nimrod and Nina accelerators.[0]
Thanks, the article written in 2020 (?) is essentially a 1 to 1 copy of the vox clip "How a recording-studio mishap shaped '80s music" from 2017.
(If the chronology is right)
kind of useless if the well produced vid delivers all the examples you can actually listen to ...
I stand corrected you are right there is no isolated use of [ɬ] in nahuatl as a phoneme it is used only in the context of an affricative /t͡ɬ/
I got ahead of myself in trying to isolate the sound [ɬ] for untrained ears.
To get back to the original point though if I'm not mistaken again in standard mexican spanish /ʃ/ as a phoneme is lost entirely and only appears in the affricative /t͡ʃ/? So in all likelihood the original /ʃ/ in axolotl would be pronounced by way of habit as [t͡ʃ] (unless again you have say a argentinian dialect where e.g. "ll" (/ʝ/) in llamar is pronounced as [ʃ]) if you try to "correct" mexican spanish speakers.
Well, actually I suppose the hardest part is to pronounce the other consonant hispanicized as -tl at the end (a soft lisp)
[ɬ]
voiceless
alveolar
lateral
fricative
[0]
in a sufficient fluent manner (except you happen to speak e.g. Welsh, there the sound is written as ll so by happenstance the "axolotl" found in Wales can be pronounced fluently by the Welsh) otherwise you are saying it half correct which is arguably worse.
So let the nahuatl speaking people have a laugh at your expense for pronouncing it the germanic way or if you want to go unnoticed do it the evolved spanish romanic way, a good middle ground I guess.
Anyway I think it is generally a lot fun to hear words pronounced "wrong" by foreigners or having trouble hearing/pronouncing it "right" respectively heavy accents are hilarious icebreakers (:
Ironically the "drama" narrative which was constructed much later making for a good story to tell could have been avoided right from the start.
Just three weeks after the publications in Nature (April 1953), a Time journalist Joan Bruce was made aware of the hottest story in science and described the discovery in her nearly publication-ready article (professional photoshoots of Watson/Crick were already taken, yes one of those pictures [0] was consequently prominently featured in The Double Helix 15 years (!) later) as a joint effort of two teams (Wilkins/Franklin & Watson/Crick) but the story was killed because apparently among other consulted scientists Franklin herself found the science lacking, it wasn't revised and subsequently no article was published at the time. No pun intended.
> Three weeks after the three DNA papers were published in Nature, Bragg gave a lecture on the discovery at Guy’s Hospital Medical School in London, which was reported on the front page of the British News Chronicle daily newspaper. This drew the attention of Joan Bruce, a London journalist working for Time. Although Bruce’s article has never been published — or described by historians, until now — it is notable for its novel take on the discovery of the double helix.
Bruce portrayed the work as being done by “two teams”: one, consisting of Wilkins and Franklin, gathering experimental evidence using X-ray analysis; “the other” comprising Watson and Crick, working on theory. To a certain extent, wrote Bruce, the teams worked independently, although “they linked up, confirming each other’s work from time to time, or wrestling over a common problem”. For example, Watson and Crick had “started to work on the double helix theory as a result of Wilkins’ X-rays”. Conversely, she wrote, Franklin was “checking the Cavendish model against her own X-rays, not always confirming the Cavendish structural theory”. It has not escaped our notice that both examples render Franklin in a position of strength, every bit a peer of Wilkins, Crick and Watson.
Unfortunately, Bruce was not so strong on the science. Her article got far enough for Time to send a Cambridge photographer, Anthony Barrington Brown, to shoot portraits of Watson and Crick, and for Watson to tell his friends to watch for it. But it never appeared, perhaps because Franklin told Bruce that it needed an awful lot of work to get the science straight. Bruce’s take on the discovery was buried, and Barrington Brown’s compelling images disappeared until Watson resurrected the best of them 15 years later, for The Double Helix.
It is tantalizing to think how people might remember the double-helix story had Bruce’s article been published, suitably scientifically corrected. From the outset, Franklin would have been represented as an equal member of a quartet who solved the double helix, one half of the team that articulated the scientific question, took important early steps towards a solution, provided crucial data and verified the result. Indeed, one of the first public displays of the double helix, at the Royal Society Conversazione in June 1953, was signed by the authors of all three Nature papers. In this early incarnation, the discovery of the structure of DNA was not seen as a race won by Watson and Crick, but as the outcome of a joint effort.
According to journalist Horace Freeland Judson and Franklin’s biographer, Brenda Maddox, Rosalind Franklin has been reduced to the “wronged heroine” of the double helix. She deserves to be remembered not as the victim of the double helix, but as an equal contributor to the solution of the structure.[1][2]
While at some point in the optimization game Goodhart’s Law will also apply here,
before that happens I thoroughly enjoyed the insights from reading it and will try implementing some version of it to gauge my productivity before jumping to another metric always aware of the abyss, the ultimate procrastination: being unproductive by trying too hard to optimize productivity.
Unproductivity is the little death that brings total obliteration.
I will face my unproductivity.
I will let it pass through me.
When it is gone, only action will remain.
What would the people who sealed the grave do when they accidentally unearthed a sophisticated burial site from the middle bronze age? Leave it alone? Maybe. I'm not sure, humans are curious.
Well the effort and care put into the grave made us - 2000 years later in cyberspace - in a sense remember the person. Who was this young woman? They even gave us hints/rewards. Made us curious.
So maybe they prepared her for an afterlife ... of continued memory and presence among the living, which they with their technological limitations succeeded in, we are talking about her, now.
> It's amazing when people flag this as a bad thing when it's undoubtedly a key component of getting places to prosperity in the first place. Got to get people away from being starvation-limited.
Exponentially falling fertility rates can create dynamics which can be destructive in its own right. As with other complex phenomena it would be for example foolish to rapidly cool the earth's climate. Stability is the key, here. Right now India is just below replacement which short to mid-term looks very promising but will it stabilize? Looking at worldwide trends I very much doubt that. A growing economy needs some demographical stability so coming from a long-term view fertility dropping off a cliff, now, could be bad news later (in one, two generations).
Turning some knobs one way or the other does not produce linear results, quite the opposite, there are thresholds, there is criticality. To draw on another more time compressed analogy here: I guess some operators thought back then: What could go possibly wrong by running a nuclear reactor (RBMK) at safer lower powers?
For me largley shaped by the westering old Europe creaking and breaking (after 2 WWs) under its heavy load of philosophical/metaphysical inheritance (which at this point in time can be considered effectively americanized).
It is still fascinating to trace back the divergent developments like american-flavoured christian sects or philosophical schools of "pragmatism", "rationalism" etc. which get super-charged by technological disruptions.
In my youth I was heavily influenced by the so-called Bildung which can be functionally thought of as a form of ersatz religion and is maybe better exemplified in the literary tradition of the Bildungsroman.
I've grappled with and wildly fantasized about all sorts of things, experimented mindlessly with all kinds of modes of thinking and consciousness amidst my coming-of-age, in hindsight without this particular frame of Bildung left by myself I would have been left utterly confused and maybe at some point acted out on it. By engaging with books like Der Zauberberg by Thomas Mann or Der Mann ohne Eigenschaften by Robert Musil, my apparent madness was calmed down and instead of breaking the dam of a forming social front of myself with the vastness of the unconsciousness, over time I was guided to develop my own way into slowly operating it appropriately without completely blowing myself up into a messiah or finding myself eternally trapped in the futility and hopelessness of existence.
Borrowing from my background, one effective vaccination which spontaneously came up in my mind against rationalists sects described here, is Schopenhauer's Die Welt als Wille und Vorstellung which can be read as a radical continuation of Kant's Critique of Pure Reason which was trying to stress test the ratio itself. [To demonstrate the breadth of Bildung in even something like the physical sciences e.g. Einstein was familiar with Kant's a priori framework of space and time, Heisenberg's autobiographical book Der Teil und das Ganze was motivated by: "I wanted to show that science is done by people, and the most wonderful ideas come from dialog".]
Schopenhauer arrives at the realization because of the groundwork done by Kant (which he heavily acknowledges): that there can't even exist a rational basis for rationality itself, that it is simply an exquisitely disguised tool in the service of the more fundamental will i.e. by its definition an irrational force.
Funny little thought experiment but what consequences does this have? Well, if you are declaring the ratio as your ultima ratio you are just fooling yourself in order to be able to rationalize anything you want. Once internalized Schopenhauer's insight gets you overwhelmed by Mitleid for every conscious being, inoculating you against the excesses of your own ratio. It instantly hit me with the same force as MDMA but several years before.
>The radiative properties of an atom in a cavity differ fundamentally from the atom's radiative properties in free space. Spontaneous emission is inhibited if the cavity has characteristic dimensions which are small compared to the radiation wavelength, and enhanced if the cavity is resonant. The cavity causes slight shifts in the energies of the atom, analogous to radiative shifts. [0]
I wouldn't classify it under radioactive decay as in "nuclear change" (here: Potassium-40 as beta minus decay and EC, respectively) as it is a well understood photon-matter-interaction phenomenona (cQED) in e.g. manipulating single photons (single atoms in cavity) deterministically [1] which can be used in turn - coincidentally - in generating true random numbers ... [2]
For anyone wondering how our bodies synchronize to a 24-hour-cycle of the earth, it is primarily through light detected by our eyes. (A great resource for in depth: Professor of Neurobiology and Ophthalmology Andrew Huberman [0])
Apart from cone (RGB) and rod cells (brightness) which are responsible for vision in general (through the "-opsin" proteins: photopsin and rhodopsin, respectively) we also have a more ancient distinctive third class (subconsciously: not taking part in any vision at all) which was first discovered in the light-sensitive skin cells of the African clawed frog in 1998:
intrinsically photosensitive retinal ganglion cells (ipRGCs), which express their own distinct opsin—melanopsin. Melanopsin cells in mammals are specialized for measuring ambient illumination, contributing to visual discrimination, and driving a wide variety of physiological responses including, but not restricted to: synchronization of circadian clocks to light : dark cycles, regulation of pupil size, modulation of sleep and suppression of pineal melatonin production.[1]
So, even if you are blind those important signalling cells could be still intact. That's why one does not remove the eyes for 'cosmetic' reasons, anymore. This circadian feedback system functions ideally when all three parts of our photoreceptors are working in unison but can still function - albeit to a limited extent - if just one part is available.
To not confuse "noons" we can categorize those in three ways:
(i) solar noon: the time when the sun is at the highest point, at a specific day, at that exact location on earth
(ii) local noon: static time-zones i.e. conventionally set. Normally within +/-2 hours of the solar noon.
(iii) biological noon: adjustable through the light from outside but without any light input it varies from person to person (a "night-day"-cycle could be anywhere from 23.5h - 24.5h long).
There are roughly three time windows in which the photoreceptors of the eyes synchronize our bodies to the outside world, the first and last being the most important ones:
(1) After our physiological temperature minimum, normally about 2 hours before we wake up, naturally. Here the "biological noon" gets set, initially. The window closes some time about that point (I couldn't find a reliable number, anywhere, my guess is about 2 hours in, so about 4 hours after the "temperature minimum" the window closes and one is locked in the "dead" zone, for now).
(2) When the sun sets down. Experiencing the change and reduction in light helps the body to anticipate and prepare for the last window.
(3) In the last phase everything gets reversed, in order to not disrupt melatonin production ("hormone of darkness and sleep initiation") it is vital to not emulate the sun (bright, overhead). The best sources of light are low-hanging warm lights and just enough brightness to feel comfortable. Here, you have to take into account the adjustment period for your eyes. Unfortunately most people aren't used to see adequately and orient themselves in low brightness settings (peripheral vision). Star-gazing could serve as a starting point for some sensibilization.
Those biological insights can be used to balance and fine-tune one's circadian rhythm.
But the most reliable and effective way in getting the system into full gear, is how this elaborate system evolved in the first place: outdoors. Living outside for a couple of days, on some weekends of the months for example, to "reset" can work wonders: a substantial set of people who think of themselves being night owls are actually fooled into it by artificial lights ;) [2]
If one looks a century back: AT&T, Xerox, IBM ... those were opportunities we can romanticize in hindsight looking back at the glowing examples of Bell Labs, PARC etc.
Today's Big Tech is unrivaled in its unique position to fund R&D.
To put it on the talent's shoulder to decide against it ...? One can hope for individual cases but it is futile as Big Tech has fundamentally tilted the playing field not only on things like information flow but also on talent pool in their favor.
From a system's POV at some point this of course gets stuck.
For example Musk tries to outpace this with his "rate of innovation" concept which on surface seems like a refreshing idea but is running on an outdated and collapsing hardware ("actual existing globalization") resulting in absurd numbers on the BBI like $243B. Leaving aside the forgone "sign-changing" and hefty "printing" by the central processors, initiated manually by a curious circle of people with access who decided it was a good idea.
> Iran waited until the clock passed midnight local time to finalize the agreement, because it did not want the momentous occasion to coincide with President Trump’s birthday on Sunday, according to two Iranian officials who could not be identified because of the matter’s sensitivity. The seven-and-half-hour time difference allowed both Tehran and Washington to claim their preferred version of when the deal was finalized. President Trump had said it would be on Sunday, and Iran had said it would be on a later day.[0]
[0]https://www.nytimes.com/live/2026/06/14/world/iran-war-trump...