This is great, thank you! I predict agentic coding will change software dramatically in this direction. I recently had my weather app showing me a full-screen video ad. It drove me so mad that I developed wwads in a few hours with claude, Weather Without Ads (or any tracking, etc.), which can be installed as a PWA on Android or iOS. https://jmrk84.github.io/wwads/
Have a look at this comment from Ken Hayworth, a highly respected scientist in the field, which I am copying here from a twitter post by him (https://x.com/KennethHayworth/status/2032604687212392562). I also just came back from the Cosyne 2026 conference, and the work was unfortunately not met with great enthusiasm, despite the media attention: My statement regarding the misleading EON Systems “fly upload” video:
The hundreds of researchers who make up the Drosophila neuroscience community are making good progress toward eventually understanding how the intelligent behaviors of a fruit fly are produced by computations in its neural circuits. Obtaining the structural connectome of the fly brain and ventral nerve cord was a significant milestone in that quest, as was obtaining an estimate of neurotransmitter types for each cell type. What is currently most lacking is a catalog of the precise electrophysiological and molecular dynamics of each neuron and synapse type. Dozens of on-going electrophysiological, genetic, and behavioral experiments are beginning to fill in those details. But completing that task will likely take many years, possibly decades, of more research. At the end of that long road, I have no doubt, there will be a detailed paper, published in a high-quality journal with full details and carefully peer-reviewed, which will at long last make the true statement “we’ve uploaded a fruit fly”. And that future paper will have a supplementary video much like the EON Systems one, showing a fly navigating a virtual environment. But, unlike the misleading EON Systems video, that future video will be real… all 100,000+ neurons displaying dynamics that reflect those that would occur in the real fly engaged in the same sensory-motor behaviors. That paper will represent the crowning achievement of a successful Drosophila neuroscience field.
What EON Systems’ misleading video and claim has done today is to try to steal that future victory and take its valor for their own, all in the hopes of raising some cash from naive investors who think they might get to human uploads soon, and all while riding a tide of hype they generated in the gullible public. The result has been a wave of secondary reporting that grossly mischaracterizes the current state of neuroscience progress, implying that it is much further along than it currently is.
As a member of the Drosophila research community, and as a long-term advocate of brain preservation for eventual mind uploading, I feel it is my responsibility to call out this reprehensible behavior. Neuroscience technology is progressing fast enough that we are now able to obtain structural connectomes of small organisms like the fruit fly. But neuroscience understanding is progressing much more slowly. True uploading, even for a fruit fly, is likely years to decades away. Even obtaining a mouse connectome seems likely to be a decade or more away. Human uploading is simply not on any reasonable research or investment timeline, unless such a timeline includes many decades of methodical basic neuroscience research. Of course, we can preserve human brains today using aldehyde fixatives as is done in all of today’s connectomics studies. But we will not be able to upload a human brain for many decades, perhaps centuries to come.
Please do not let today’s real scientific progress in connectomics and brain preservation be drowned out by misleading hype.
Great idea; I just picked IMAP because I thought it'd be somewhat universal. I hadn't heard of JMAP before. It should be quite straightforward to integrate. FastMail actually also seems to support IMAP.
I got tired of “email archaeology”; digging through years of inboxes to find something I know is in there.
So I built NeuralMail: a fully open-source tool that makes your email (IMAP accounts) searchable with LLMs. It’s not an email client, just a way to extract and query info, no fuss.
Works with any IMAP provider (Gmail, Outlook, etc.), no lock-in.
Searches across multiple accounts at once
Handles 10k–100k+ emails, even attachments
Lets you plug in any LLM (local or API) so you can choose between privacy vs performance
Originally a weekend project (started CLI-only), but after a few months of use it’s become indispensable for me.
I think when you remove ingroup and outgroup and just keep the argument for the attitude toward yourself/others it becomes more obvious what I mean. Otherwise it really depends on where you draw the boundary for the ingroup (e.g. your close family)/outgroup (e.g. your neighbors) which leaves a lot of room for interpretation.
Well, I think my optimum is just a hypothetical high-trust society in which everyone strives to be self-sufficient but gets supported in case of failure by others. Of course, this is not how the world works, which is more what you are describing. I don't think that is best though, from the perspective of humanity.
Very interesting comment, not because I agree with it, but I think it exposes a classic left vs right wing problem, and that the attitude is applied universally instead of selectively. IMO, the optimal attitude for society would be if everyone was "left-wing" (generous, forgiving,...) toward others/out-groups and "right-wing" (demanding, requesting responsibility,...) toward yourself/in-group.
Very interesting read. I interpret this in the way that clustering (eg HDBSCAN) on UMAP-projected data makes some sense at least (contrary to tSNE), are there any differing opinions on this? Interesting related discussions: https://stats.stackexchange.com/questions/263539/clustering-...
The recent NIH brain initiative report describes the acquisition of a synaptic resolution connectome of an entire mouse brain using massively parallel electron microscopy. The 5 year plan seems a bit too optimistic to me, especially due to remaining difficulties in staining technology, but if successful, the project will definitely transform neuroscience.