Could a vaccine prevent dementia? Shingles shot data only getting stronger(arstechnica.com)

11 pointsby jnordhace 5 meses1 comments

Could a vaccine prevent dementia? Shingles shot data only getting stronger

https://arstechnica.com/health/2026/02/could-a-vaccine-prevent-dementia-shingles-shot-data-only-getting-stronger/

2 comments

bikenagahace 5 meses

Ars's recent issues with fabricated quotes were very disappointing. But Beth Mole is consistently excellent. She has a PhD in microbiology, and is a very careful writer. In the linked article, she cites the following studies. The evidence for a reduced dementia risk seems pretty convincing, particularly given the "natural cutoff" studies:

    * Cited research: "Herpes zoster vaccination and the risk of dementia: A systematic review and meta-analysis" - https://pubmed.ncbi.nlm.nih.gov/38687552/
    * Cited research: "A natural experiment on the effect of herpes zoster vaccination on dementia" - https://www.nature.com/articles/s41586-025-08800-x
    * Cited research: "Herpes Zoster Vaccination and Dementia Occurrence" - https://jamanetwork.com/journals/jama/fullarticle/2833335?
    * Cited research: "Herpes zoster vaccination and incident dementia in Canada: an analysis of natural experiments" - https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00455-7/fulltext
    * Cited research: "The recombinant shingles vaccine is associated with lower risk of dementia" - https://www.nature.com/articles/s41591-024-03201-5
    * Cited research: "Recombinant zoster vaccine is associated with a reduced risk of dementia" - https://www.nature.com/articles/s41467-026-69289-0
    * Cited research: "Association between shingles vaccination and slower biological aging: Evidence from a U.S. population-based cohort study" - https://academic.oup.com/biomedgerontology/advance-article/doi/10.1093/gerona/glag008/8430804?login=false

antibullhace 5 meses