I know someone with what we thought was MCAS, but it actually ended up being Alpha-gal Syndrome. Knowing that made the whole thing much easier to deal with.
I know someone with what we thought was MCAS, but it actually ended up being Alpha-gal Syndrome. Knowing that made the whole thing much easier to deal with.
The thing with all these autoimmune diseases: they have the same foundational problem. Their is something in the blood that doesn’t belong there and it resembles some part/cell of our body. Our body builds white blood cells to destroy this thing and inadvertently destroys part of the body. The important questions: what is it and how is it getting into the blood?
The most likely way it gets into the blood is through the digestive track. Some possible mechanisms:
1. Some detergent or similar chemical (e.g. PFAS is a solvent) dissolves the food (or the oil carrying the food) into water. The stomach pulls water back into the blood stream, bringing dissolved things with it.
2. There is some damage to the stomach or intestinal lining, stemming from physical injury, things getting stuck (lack of fiber), acid damage, some other chemical destroying mucus lining, etc.
3. You also have some autoimmune damage on your intestines.
4. You eat certain foods that require a symbiotic digestion with gut bacteria, but lack that bacteria or have killed it with eating preservatives or pesticides or artificial sweeteners, etc. The undigested food makes it to the larger absorption holes at the end of the intestinal run.
It’s also possible that a brain injury caused some brain cells to end up in the blood stream. Normally, though, the body has a mechanism to avoid attacking its own cells, the CD47 mechanism. Maybe that can become damaged or malnourished in some way. I’m sure that there’s a host of other things that can go wrong with that.
I'm not saying the article is wrong, but here's why I think we've struggled to have the year of the Linux Desktop: the corporations want control over users and computers that are on the network. They like their Windows domain user and computer GUI controls, that let them add/remove users and computers at will. They like the control of that centralized management. Centralized user management is more work on Linux, and tools for it aren't as pretty. The Hypervisor GUI is another tool that executives like to see.
AMC should start showing Chinese and Korean dramas. That would help them a lot. I'm sure that they could work a deal with those studios that would let AMC set the ticket price. There hasn't been an American-made movie since Lord of the Rings that has compelled me to go see it in the theater. The movie studios seem to be pushing more extremes on immorality, violence, gore, etc, being completely disconnected from the average American's values. And then Disney and others make musicals with actors that can't sing -- mind-boggling. Hence, my wife and I watch Chinese dramas instead, a few episodes per week being my complete TV/Movie intake. They're paced better, develop characters, include a few kung fu moves, have nice visuals, aren't afraid of religious topics, etc.
The whole place-and-route thing is completely wrong for using FPGAs as accelerators. We don't need an optimal layout, we need a tiled layout (like the GPU does). All that we need for this to happen is for the companies making the FPGAs to open up the board layout file spec. They don't need to even make/ship any software at all. Just ship the dang file that says where the resources & timings are and some instructions on how to toggle the LUT config.
My feeling is that hardware companies do better when they ship the software needed to utilize their hardware for free. (You need a little margin in the hardware price to cover the software development). However, the FPGA companies haven't figured this out. They try to make way too much software and charge exhorbitant fees for it, somehow thinking that their hardware is useless without that. In fact, their hardware is useless because I can't put anything on it without a 1-to-20 hour compile time. That makes it impossible to use it as an accelerator. I can compile OpenCL for my GPU in a few milliseconds; that's what we need for the FPGA. Even thirty seconds would be easily tolerable -- there's many a game that still requires 15 seconds to load a level and compile its shaders.
FPGAs could be much more useful than they are at present. They've artificially limited themselves to ASIC prototyping alone.
So Intel bought an FPGA company -- nobody knows why. AMD got scared and did the same thing with no clue what to do with it. They've both let them rot. Intel did start incorporating it into its compiler targets, but it was only half-baked. Now they've wisely divested themselves of the company, but it should have never happened. They should have just focused on selling the hardware at a small margin whilst opening up the data to use it.
Note: please don't turn your screenshots and digital art into JPG. JPG uses compression based on natural lighting. It works well for photos, but it's the wrong solution where run-length encoding will do much better (e.g. in screenshots). Black text (or cartoon art) on white backround always looks lousy when converted to JPG.
This book has software engineering concepts that I never did see or hear anywhere else: "Expert C# Business Objects". Its concepts are language agnostic, even though it has C# examples. You might try some videos by the author of that book too.
Related to this book is what we call "vertical feature slicing". (I'd be curious to know what other books cover this topic.) There are some Youtube videos on the topic. There was a great 2-hour video from 20 years ago that influenced me. Unfortunately, I don't remember the title and cannot find it today.