HackerTrans
TopNewTrendsCommentsPastAskShowJobs

admeyer

no profile record

Submissions

Pre-print: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2

twitter.com
2 points·by admeyer·hace 4 años·0 comments

Idea: Amazon gives full Kindle copy to expire when hard copy book delivers?

8 points·by admeyer·hace 4 años·5 comments

comments

admeyer
·hace 7 meses·discuss
[flagged]
admeyer
·hace 4 años·discuss
I remember this bundling program. This would be similar but just cover the gap between order and delivery. Full copy of Kindle would disappear when hard copy is marked delivered.
admeyer
·hace 4 años·discuss
Make it a Prime benefit.
admeyer
·hace 4 años·discuss
I read book samples on the Kindle app, and then order the hard copy if it’s good. It struck me that it would be amazing if Amazon gave me the full Kindle version until the hard copy book delivers. I ordered hard copy Saturday and it doesn't deliver until Wednesday. A long wait for a page-turner.
admeyer
·hace 4 años·discuss
We get a lot of eggs from our neighbors and other local egg producers who put a lot of effort into raising healthy chickens. In addition to a deep-colored yolk I like to see how tall the yolk sits in the pan. For freshness, you might see thin, white ropes trailing from the yolk called chalazae.
admeyer
·hace 4 años·discuss
LINE-1 comprise something like 17% of the human genome according to early work by Eric Lander and team. They also have a fascinating interplay with HIV and Interferon Signaling System: https://www.frontiersin.org/articles/10.3389/fimmu.2021.7327...
admeyer
·hace 5 años·discuss
Paragraph near the bottom of Reuters article on Molnupiravir states:

"Merck has said data shows molnupiravir is not capable of inducing genetic changes in human cells, but men enrolled in its trials had to abstain from heterosexual intercourse or agree to use contraception. Women of child-bearing age in the study could be pregnant and also had to use birth control."

Link to said Reuters article: https://www.reuters.com/business/healthcare-pharmaceuticals/...

What do you suppose would happen?
admeyer
·hace 5 años·discuss
“Our strategy begins by a complete inventory of bats and their SARSr-CoVs at our intervention test site cave complex in Yunnan, China that harbours bats with high-risk SARSr-CoVs. We will collect data from three caves in that system (one is our intervention test site and two control sites) on: monthly bat abundance and diversity, viral prevalence and diversity, individual bat viral load and host physiological markers; and genomic characterization of low- and high-risk SARSr-CoV strains among bat species, sexes, and age classes; satellite telemetry and mark-recapture data on bat home range and inter-cave movement; and monitoring of daily, weekly and seasonal changes in bat populations.” (D1, p.5)

“However, our test cave site in Yunnan Province, harbours a quasispecies (QS) population assemblage that contains all the genetic components of epidemic SARS-CoV34, We have isolated three strains there (WIV1, WIV16 and SHCO14) that unlike other SARSr-CoVs, do not contain two deletions in the receptor-binding domain (RBD) of the spike, have far higher sequence identity to SARS-CoV (Fig. 1), use human ACE2 receptor for cell entry, as SARS-CoV does (Fig. 2), and replicate efficiently in various animal and human cells.” (D1, p.7-8)

Lovely.