this.
It doesn't matter one whit about the instance, except perhaps initially. Maybe.
You choose who to read and follow and the instance doesn't matter.
I already 'follow' about 80 like-minded geeks I'm interested to read each day and that's all I can keep up with.
I never look at either the local timeline or the federated timeline: they are too much information; firehose.
edit: and those 80-odd ppl are all over the planet on various instances in various languages.