Teenage Engineering gear is not meant to last. It is an illusion created by how their product looks like and how it is marketed. Once the warranty expires, you won't be able to repair products like TX-6. I've gotten bitten by that myself. TE does not really provide much support to its users to help them maintain and repair this expensive gear.
The defaults are absolutely sane. I've been using FreeBSD with root on ZFS on all sorts of workstations and laptops for many years now. It's always run just fine, even on cheap laptops with 2 GB of RAM.