I don't have a mac, let alone a silicon one, so I can't test on it (I also have no patience for Apple's BS). However, it should work. At least SBCL itself runs, and Trial is mostly portable code, so it should, too, modulo some regressions.
I specifically talk about the fast evaluator for SBCL. But even without that contrib, SBCL does have another evaluator as well that's used in very specific circumstances.
The OS can do it, and some Nintendo titles on the Switch do use this capability, but I have talked to Nintendo directly about using it, and it's a hard No. I can't even use the JIT feature purely for dev.
My current unannounced project is a lot more ambitious still, being a 3D hack & slash action game. I post updates about that on the Patreon if you're interested.
You cannot publish games with homebrew, it has to use the official SDK. Besides that, almost nobody has a jailbroken Switch, so it would make it extremely hard to play any games on anything but an emulator.
I'm not doing the SBCL parts, that's all Charles' work that I hired him for. My work is the portability bits that Trial relies on to do whatever and the general build architecture for this, along with the initial runtime stubbing.