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dddiaz1

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Analyzing my own genome with DRAGEN and Claude

dddiaz.com
1 points·by dddiaz1·il y a 6 mois·1 comments

Enabling Rapid Genomic Analysis with Illumina Dragen on Amazon EC2 F2 Instances

aws.amazon.com
1 points·by dddiaz1·il y a 12 mois·0 comments

Genomic Adventures: Exploring the Genetic Roots of My Type 1 Diabetes in My DNA

dddiaz.com
1 points·by dddiaz1·il y a 2 ans·0 comments

Installing my own open source pancreas

dddiaz.com
1 points·by dddiaz1·il y a 3 ans·0 comments

Halloween Spooktacular: Fog Machine Madness

blog.apartment304.com
3 points·by dddiaz1·il y a 3 ans·0 comments

Illumina Complete Long Reads software analysis workflow

illumina.com
1 points·by dddiaz1·il y a 3 ans·0 comments

The Amgen vs. Sanofi Decision and Bite-Sized Monopolies

patentlyo.com
2 points·by dddiaz1·il y a 3 ans·0 comments

The Era of Fast, Cheap Genome Sequencing Is Here

wired.com
3 points·by dddiaz1·il y a 4 ans·0 comments

comments

dddiaz1
·il y a 6 mois·discuss
https://dddiaz.com/

Blog about Genomics, Type 1 Diabetes, and Life.
dddiaz1
·il y a 2 ans·discuss
Great to see it be OTC. But it's weird that it is advertised to last for 15 days, while the prescription version for T1ds/T2ds only lasts for 10 days. The hardware looks the same.
dddiaz1
·il y a 2 ans·discuss
Very Cool!

I also have T1D and its a natural source for cool software engineering projects like this.

You might like these two posts: Using machine learning to predict when I excercised: https://dddiaz.com/post/glucose-datascience/

Using Genomic Software to explore my auto-immune genes: https://dddiaz.com/post/hla/
dddiaz1
·il y a 3 ans·discuss
If you are interested in genomics, some other reads I recommend:

The Gene: An intimate history. An incredible retelling of how we discovered the gene, from Mendel and his pea plants to next generation sequencing. https://www.amazon.com/Gene-Intimate-History-Siddhartha-Mukh...

The Genome Odyssey A series of patient stories documenting the process of using genomics to diagnose and treat rare diseases in patients https://www.amazon.com/dp/1250234980

The author of this article, nick lane also has some popular bio books, in particular: Transformers, The deep chemistry of life. https://www.amazon.com/Transformer-Deep-Chemistry-Life-Death...
dddiaz1
·il y a 3 ans·discuss
Another really cool use case for FPGAs is for ultra fast analysis of genomic data. This guide walks you through setting up an F1 instance (AWS FPGA) to do that: https://aws-quickstart.github.io/quickstart-illumina-dragen/
dddiaz1
·il y a 4 ans·discuss
I have absolutely loved working in genomics. I am a huge believer that genomics will be a huge part of healthcare in the future, and i have two examples to motivate that point that I think may be interesting to the reader.

1) The Moderna vaccine was made with the help of illumina genome sequencing. They were able to sequence the virus and send that sequence of nucleotides over to moderna for them to develop the vaccine - turning a classically biology problem, into a software problem, reducing the need for them to bring the virus in house.

2) Illumina has a cancer screening test called Galleri, that can identify a bunch of cancers from a blood test. It identifies mutated dna released by cancer cells. This is huge, if we can identify cancer before someone even starts to show symptoms, the chances of having a useful treatment dramatically go up.

Disclaimer: I work for illumina, views my own.

I wrote some more about why genomics is cool from a technical point of view here (truly big data, hardware accelerated bioinformatics) : https://dddiaz.com/post/genomics-is-cool/