Maybe, but having wires coming out of the same side as the pointing device is annoying. For cost reasons you have to pick one side. So put it where it causes less issues.
I went to school at Michigan Tech where we would regularly get over 300 inches in the winter. I drove a Honda civic with snow tires. It was fine even on steep slopes. Winter tires keep you from loosing traction and sliding off the road. AWD helps you get back on the road after you slide off.