HackerLangs
TopNewTrendsCommentsPastAskShowJobs

wordglyph

no profile record

Submissions

I pitched a roller coaster to Disneyland at age 10 in 1978

wordglyph.xyz
561 points·by wordglyph·il y a 5 mois·200 comments

comments

wordglyph
·il y a 2 mois·discuss
Nice job! I just recently coded my word game into an app of your on desktop you can still play it. Wordglyph.xyz
wordglyph
·il y a 2 mois·discuss
are your mail servers whitelisted with the big players.
wordglyph
·il y a 4 mois·discuss
have you considered Replace X25519 with a post quantum cryptography key encapsulation mechanism like kyber or saber?
wordglyph
·il y a 4 mois·discuss
What do you think about https://app.sesame.com/
wordglyph
·il y a 5 mois·discuss
Good insight. Yes, I do remember at the time, purposely thinking I must lead with my age knowing instinctively that somehow that would help me and they would be more likely to pay attention.
wordglyph
·il y a 5 mois·discuss
You do realize they already are investigating, right? Even looking into MS and parkinson. ALZHEIMER’S DISEASE (AD) and AD DEMENTIA Umbrella review (systematic reviews of SRs): https://www.nature.com/articles/s44400-025-00048-6

Systematic review + meta-analysis (basal microbiota; AD): https://alz-journals.onlinelibrary.wiley.com/doi/abs/10.1002... https://pmc.ncbi.nlm.nih.gov/articles/PMC11672027/

Replicated case-control + functional metagenomics (AD dementia): https://alz-journals.onlinelibrary.wiley.com/doi/full/10.100...

Large-cohort metagenomics (stage-specific / early pathology signals): https://pubmed.ncbi.nlm.nih.gov/40164697

Mendelian randomization (AD): https://pubmed.ncbi.nlm.nih.gov/38788075/ https://www.sciencedirect.com/science/article/pii/S227458072... https://pubmed.ncbi.nlm.nih.gov/40665707/ https://journals.sagepub.com/doi/10.1177/25424823261422629 https://www.medrxiv.org/content/10.1101/2025.08.20.25333769v...

Narrative / mechanisms (useful synthesis, not primary causal proof): https://www.sciencedirect.com/science/article/abs/pii/S15681...

MILD COGNITIVE IMPAIRMENT (MCI) / DEMENTIA (cognition-focused evidence) Systematic review (MCI or Alzheimer’s dementia; PRISMA, PROSPERO): https://www.mdpi.com/2035-8377/17/10/155 https://pubmed.ncbi.nlm.nih.gov/41149776/

Scoping review (MCI and AD gut microbiomes + interventions, through Feb 2023): https://pmc.ncbi.nlm.nih.gov/articles/PMC12825029/

Systematic review of microbiota-targeted interventions for cognition/dementia risk: https://www.sciencedirect.com/science/article/pii/S027153172...

RCT-focused systematic review/meta-analysis of probiotics for cognitive impairment risk/AD/MCI: https://pmc.ncbi.nlm.nih.gov/articles/PMC12645680/

FMT in dementia/MCI context (review of effects across neuro cohorts): https://www.sciencedirect.com/science/article/pii/S266635462...

MULTIPLE SCLEROSIS (MS) Microbiome signatures via global data integration / ML: https://pmc.ncbi.nlm.nih.gov/articles/PMC12383397/

Systematic review/meta-analysis of probiotics in MS (preclinical + clinical): https://journals.plos.org/plosone/article?id=10.1371/journal...

Systematic review + meta-analysis (antimicrobial exposure and MS risk; microbiome-disruption relevant): https://www.sciencedirect.com/science/article/abs/pii/S22110...

Mendelian randomization (gut microbiota causally linked to MS): https://pubmed.ncbi.nlm.nih.gov/39065244/ https://www.mdpi.com/2076-2607/12/7/1476

Broad MS gut dysbiosis and therapeutic modulation review: https://pmc.ncbi.nlm.nih.gov/articles/PMC12668904/

MS gut-brain-barrier and intestinal barrier review: https://www.frontiersin.org/journals/immunology/articles/10....

Example MS cohort biomarker/signature work: https://www.nature.com/articles/s41598-024-64369-x https://www.nature.com/articles/s41598-025-19998-1

PARKINSON’S DISEASE (PD) Multi-cohort metagenomic meta-analysis (Nat Commun, 2025): https://www.nature.com/articles/s41467-025-56829-3 https://pubmed.ncbi.nlm.nih.gov/40335465/

Large metagenomics cohort (Nat Commun, 2022): https://www.nature.com/articles/s41467-022-34667-x

Integrated multi-cohort gut metagenome (Movement Disorders, 2023): https://pubmed.ncbi.nlm.nih.gov/36691982/ https://movementdisorders.onlinelibrary.wiley.com/doi/10.100...

Metagenomic analysis (Movement Disorders, 2024): https://pubmed.ncbi.nlm.nih.gov/39192744/

PD causal-inference and MR discussion (review-type synthesis): https://pmc.ncbi.nlm.nih.gov/articles/PMC12512240/

MR study example (PD gut microbiota): https://journals.lww.com/md-journal/fulltext/2025/10310/caus...
wordglyph
·il y a 5 mois·discuss
Your gut bacteria is the prevention and the cure.
wordglyph
·il y a 5 mois·discuss
He sent the letter in April 1979! He was only 3 months into the job.
wordglyph
·il y a 5 mois·discuss
Note to self. Build time machine and fix this.
wordglyph
·il y a 5 mois·discuss
That's amazing!
wordglyph
·il y a 5 mois·discuss
Is any content generated by ai?
wordglyph
·il y a 6 mois·discuss
This is fantastic! I've been doing this manually for years. My main focus is always what does the research show about xyz supplement on gut bacteria.
wordglyph
·il y a 6 mois·discuss
Removal worked well but it always downloads a white background no matter if I chose transparent
wordglyph
·il y a 8 mois·discuss
Integrating AI browser stuff is very cool!
wordglyph
·il y a 8 mois·discuss
Are you planing to make a web version for mobile?
wordglyph
·il y a 8 mois·discuss
It be fun it you could swipe the rows in the direction you want on mobile
wordglyph
·il y a 8 mois·discuss
Fun! How do you turn off the sound? And you like challenging word games then check out my game https://wordGlyph.xyz
wordglyph
·il y a 8 mois·discuss
It requires email and payment info to get free trial.
wordglyph
·il y a 8 mois·discuss
Is this running thru your own servers you control? What country are they based in? What is the pricing after 15min? And what methods of payments do you accept?
wordglyph
·il y a 9 mois·discuss
I used aistudio and it understood pitch and and even emotion with an uploaded mp3