Intrarectal perfluorodecalin for enteral ventilation in a first-in-human trial(cell.com)

6 pointsby surprisetalk7 bulan yang lalu2 comments

Intrarectal perfluorodecalin for enteral ventilation in a first-in-human trial

https://www.cell.com/med/abstract/S2666-6340(25)00314-9

3 comments

aitchnyu7 bulan yang lalu

1 liter can contain upto 490ml oxygen but supplemental oxygen is upto 60 liters per minute. Do they plan to put a bubbler to replenish oxygen? And did they compute maximum oxygen transfer for the intestines?

They administered a "dose of non-oxygenated perfluorodecalin" but there is "oxygenation effect" observed. How?

jfengel7 bulan yang lalu

Sounds like they were testing just for safety, rather than effect. It would be interesting to see if they tried holding their breaths.

In the image, the "self directed excretion" looks distressing.

robertmp7 bulan yang lalu