I think in the near future we'll have deep neural nets that create and puppet an VR avatar for us, while we're sitting normally in front of our PCs. Kind of like a recursive version of a v-tuber: you pretend you're wearing a VR headset and listen to the pointless rambling during meetings, while your boss pretends that everyone is being so much more productive.
I think Guix is more than ready for providing development environments, even for proprietary apps on open source technology stacks (but Nix will probably be easier to pitch). As an operating system much less so.