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jerkstate

2,493 karmajoined 10 tahun yang lalu

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FDA: Use of Bayesian Methodology in Clinical Trials

fda.gov
1 points·by jerkstate·6 bulan yang lalu·0 comments

comments

jerkstate
·22 jam yang lalu·discuss
it interleaves the end note in the text at the point where the endnote is referenced (by number), reads the endnote, and then sounds a bell to indicate that we've returned to the main text.

Sometimes endnotes reference other endnotes and you have to wait until the point in the text, e.g. endnote 304 is referenced from earlier endnotes than it occurs in the text (rather late in the book) and you just have to wait until endnote 304 is read to find out what it is. that's a bit of a disadvantage, but infinite jest is the kind of book that you really need to read multiple times in order to get it anyways.
jerkstate
·22 jam yang lalu·discuss
if you're interested in completing it, check out the 30th anniversary audiobook, it just came out a few months ago, very accessible
jerkstate
·22 jam yang lalu·discuss
I visited this and several other Gaudi buildings about 15 years ago in Barcelona, and many of them are truly breathtaking, or at least dramatically original and unique. I went to the Gaudi museum as well and found it fascinating that the architect himself was not a professional mathematician - he did not use hyperbolic cosine to calculate the dimensions of the catenary curves, he traced the outline of hanging chains. Really interesting to hear about how he also heavily used ratios and symmetry. I love how artistic taste can be partially derived from math (but the math itself isn't sufficient to develop artistic taste)
jerkstate
·kemarin dulu·discuss
It’s definitely got AI tells, and I understand the objection - it’s hard to tell the difference between slop (written without review or direction, meant to fill space or present a simulacra of information) and actual informational content. With this article, it was clear that the author wanted to describe what problems they had and how they overcame those problems, and it was concise and I could tell it was reviewed so the content seemed trustworthy to me. I understand that some people have pretty high standards - if you don’t have the time to type out all of the code yourself one character at a time, then write stylish, interesting prose about it one letter at a time, if all you want to do is solve interesting problems and communicate how you solved them, you should shut up until you get good. Me, I am also imperfect and lazy, so I don’t care to demand style points or demonstrations of perspicacity from others.

Thanks for posting this, OP, I thought it was interesting.
jerkstate
·4 hari yang lalu·discuss
> In some ways, the concentration of power in a dictatorship might be better, if the dictator was well morally aligned with the people.

This is pretty much the exact argument that Hayek makes - socialism leads to fascism through political gridlock.
jerkstate
·16 hari yang lalu·discuss
[flagged]
jerkstate
·16 hari yang lalu·discuss
It’s time for people who understand how to use AI to stop trying to convince people who don’t. Let them churn their own butter, weave their own clothes, and type out their programs one character at a time. It’s what they want.
jerkstate
·bulan lalu·discuss
How do you know those aren’t the same thing?
jerkstate
·bulan lalu·discuss
Their cohort studies are across three completely different populations. I would be willing to listen to an argument that for some specific population there’s a firearm ownership level above which there are diminishing safety returns, but I find the idea that this same level would hold across wildly different populations absurd
jerkstate
·bulan lalu·discuss
Try the audiobook, although I’m sure purists would consider it cheating. You can zone out and it keeps going and something will pull your attention and you can rewind to get the context.
jerkstate
·bulan lalu·discuss
How do you know what volitions and abilities it doesn’t have? My agent teams continually improve the process and tooling they use for teamwork
jerkstate
·2 bulan yang lalu·discuss
https://en.wikipedia.org/wiki/Socratic_method
jerkstate
·2 bulan yang lalu·discuss
Get a sleep study done to find out how serious it is
jerkstate
·2 bulan yang lalu·discuss
Do you consider it humanitarian to further weaken a nation where the average gdp per capita is less than $3000 and who are in no way a threat to us? In what way do the immigrants arriving from there improve America? Can you give a coherent argument? I can easily argue the opposite from statistics:

From Census Bureau’s American Community Survey (ACS) and Annual Social and Economic Supplement of the Current Population Survey (ASEC CPS):

Of Haitian immigrants ages 25 to 64, 17.1 percent have not graduated from high school, 30.3 percent have only a high school degree, 30 percent have some college, and 22.6 percent have at least a college degree. This compares to 6.6 percent, 25.4 percent, 30.4 percent, and 37.6 percent for U.S.-born Americans. (2022 ACS)

Of households headed by Haitian immigrants, 52.7 percent use at least one major welfare program. For households headed by native-born Americans it is 28.4 percent.5 (2023 ASEC CPS)

So it’s clear that the previous immigration regime that allowed this was optimizing for something other than improving America or intentionally weakening rival countries.
jerkstate
·2 bulan yang lalu·discuss
Are you implying that we should be trying to weaken Haiti?
jerkstate
·2 bulan yang lalu·discuss
What about the immigrant groups that don’t dramatically out-earn American-born citizens?
jerkstate
·2 bulan yang lalu·discuss
So what prevents the incompetent and lazy from immigrating?
jerkstate
·2 bulan yang lalu·discuss
so in order to increase our median intelligence, we should make the process super easy?
jerkstate
·2 bulan yang lalu·discuss
[flagged]
jerkstate
·2 bulan yang lalu·discuss
It’s a shame they were so anti-nuclear. Best song on that album was Ohm Sweet Ohm.