Historically it's been up and down. It will go away for a while. There's also archive.today and archive.ph . Sometimes it gets firewalled by zealous sysadmins.
Human tissues may be fine tuned to need a specific range of C12orf29 molecule quantities: too many or too few might be big problems. See https://www.proteinatlas.org/search/C12orf29 for the gene expression for various tissues.
Renaissance Technologies: "Renaissance's flagship Medallion fund, which is run mostly for fund employees,[10] is famed for the best track record on Wall Street, returning more than 66 percent annualized before fees and 39 percent after fees over a 30-year span from 1988 to 2018"[0]
[0] https://en.wikipedia.org/wiki/Renaissance_Technologies
> feeding mice with high fat diets gives them a kind of Alzheimer disease.
Do you have a link for this.
I found this:
"However, some of these diets contain levels of dietary fat that are much higher than the levels that humans routinely consume. The question has been raised as to whether experimental use of these diets with very high levels of fat adequately models the situation of human obesity."
https://www.nature.com/articles/s41366-019-0363-7