Japanese scientists working on creating human eggs and sperm in the lab(npr.org)
npr.org
Japanese scientists working on creating human eggs and sperm in the lab
https://www.npr.org/sections/health-shots/2023/09/28/1200105467/japanese-scientists-race-to-create-human-eggs-and-sperm-in-the-lab
149 comments
I never knew there was such an industry surrounding IVF until researching it. It's wild how hush hush and not talked about it is while simultaneously common enough there's a whole medical tourism industry for it. You can have prescriptions sent to you in advance, get picked up by a driver at the airport and stay at an affiliated beach resort. They'll deliver prescriptions to your room so you don't need to go to pharmacy in a foreign country. Hell, some providers even include a working SIM card in the package.
There's nothing quiet about it. There's a whole district near where I live dedicated to it, it's covered by my health insurance, I've contracted to an IVF company here to do ML for face matching, many of my friends have used it, it's well enough known that the acronym didn't need to be defined.
Pardon my ignorance, but they use ML to find sperm and egg donors that match similar facial features to the “parents”? Cause that is honesty pretty cool.
If you're talking about DNA, yes, but no. I've worked on that too and it's much harder. In the above instance we used photos of the donors and customers and the typical case was to get a close match for the partner who was shooting blanks in order to produce an offspring who ideally would look like both "parents".
That is really awesome, would you happen to know how effective the photo method is? As in, do the kids end up looking similar to their “parents”?
I couldn't imagine an ML project where you have to wait 10-15 years before finding out if the results were good enough!
It’s old knowledge that parents (more typically fathers) bond with newborns that look like them, so you could have results within a year and again within 5 when the child looks more like their adult selves
> I've contracted to an IVF company here to do ML for face matching
This is actually a good idea. I have a hard time believing it actually performs well though
This is actually a good idea. I have a hard time believing it actually performs well though
I'm in Canada. It is a bit of an awkward topic, but turns out half of families I know had some sort of fertility treatment. Whether just some pills to help out with hormones or sperm count, or IUI, or IVF. It's covered by provincial insurance and is a medical procedure like any other.
As our fertility challenges increase (from biological issues like decrease in male sperm counts and fertility to social ones like longer student loans, getting together later, and strong emergence of non-cis-hetero families), it seems increasingly a must to preserve a modern society at least in the Interim. But yeah, people don't / didn't talk about it much. A lot of older generations or particularly zealously religious still don't - we like to find exciting ways to taboo and isolate each other :-/.
As our fertility challenges increase (from biological issues like decrease in male sperm counts and fertility to social ones like longer student loans, getting together later, and strong emergence of non-cis-hetero families), it seems increasingly a must to preserve a modern society at least in the Interim. But yeah, people don't / didn't talk about it much. A lot of older generations or particularly zealously religious still don't - we like to find exciting ways to taboo and isolate each other :-/.
Big if it works for fertility treatments. No more need for ovary stimulation and ultrasound guided egg retrieval (painful and complications can occur), and the math and need around reproductive tissue cryostorage changes for the positive.
Despite the concerns, the Japanese government is considering allowing scientists to proceed with creating IVG embryos for research.
Fujita, who's on the committee the government formed to consider this, supports that.
"The technology of IVG, its purpose is not only [to] have a baby — genetically related baby — but there are many benefits and good things you can know from the basic research," she says, such as finding new ways to treat infertility and prevent miscarriages and birth defects.
Fujita, who's on the committee the government formed to consider this, supports that.
"The technology of IVG, its purpose is not only [to] have a baby — genetically related baby — but there are many benefits and good things you can know from the basic research," she says, such as finding new ways to treat infertility and prevent miscarriages and birth defects.
I'm really curious how the bioethicist debate around this would work. At some point it feels like you're experimenting on humans without their consent. I guess that can be said about many treatments that are used to make babies (like IVF) or otherwise affect the young, but given the inherent uncertainty that would surround the first couple human babies that would be made using this technique, it does seem like a pretty wide bridge to cross.
Mixing two parents genes randomly and then seeing what happens (ie, normal human reproduction) is also experimenting on a future human without their consent.
Applications of ideas around consent to human reproduction are confusing and self-contradictory at the best of times.
Applications of ideas around consent to human reproduction are confusing and self-contradictory at the best of times.
Except they're not mixing two parents genes randomly. Moreover, we know for a fact that not receiving male genes or not receiving female genes is problematic (see Angelman and Prader-Willi syndrome... genes must be received from one man and one woman, and women cannot produce male haploid genes and vice versa). In general, the only thing humans have tried is randomly mixing a man and a woman's genes, not two random people.
Of course they are: The parent's genes are mixed randomly. Every child is the non-consenting participant in a randomized trial. That the structure of the experiment being run is standardized does nothing to change this fundamentally uncontrolled character.
Which is ethically fine by me! I'm just pointing out that reproduction is one of the areas where the limitations of consent based bioethics are blindingly obvious.
Which is ethically fine by me! I'm just pointing out that reproduction is one of the areas where the limitations of consent based bioethics are blindingly obvious.
My point is that the parents are a man and a woman and this is talking about potentially two men and two women. We know that if these things happen randomly (two genes inherited from one parent, even if from the other chromosome), that it causes severe developmental problems.
The genes in sperm are physically different than those in eggs. It's called methylation and I gave you an example of a disease caused by it going wrong.
The genes in sperm are physically different than those in eggs. It's called methylation and I gave you an example of a disease caused by it going wrong.
I never said anything about the likely safety of the technology, so I'm not sure what that has to do with it?
The genetic mix from parents is randomized. Always. Both good and bad results are equally the result of a random process initiated by the parents. A combination of recessive genes to cause disease is not more or less random than a combination of healthy genes. The parents roll the dice, the child gets the result.
In other words: The ethics can't proceed from first principles around consent to experimentation. It has to include, as you say, empirical questions about the technology in question. But that's a different sub-thread.
If I had to say anything about that: I think this is one of those things that is just going to happen whether or not anyone likes it. The fact that it has already succeeded with mice + the massive applications... it's just going to get tried, it's just a matter of which country it happens in. The fact that it could potentially be used by same sex couples is a total side note to how strongly this will be pulled along by the same existing demands that drive IVF currently, the potential is just too powerful. So I imagine we're just going to see eventually.
The genetic mix from parents is randomized. Always. Both good and bad results are equally the result of a random process initiated by the parents. A combination of recessive genes to cause disease is not more or less random than a combination of healthy genes. The parents roll the dice, the child gets the result.
In other words: The ethics can't proceed from first principles around consent to experimentation. It has to include, as you say, empirical questions about the technology in question. But that's a different sub-thread.
If I had to say anything about that: I think this is one of those things that is just going to happen whether or not anyone likes it. The fact that it has already succeeded with mice + the massive applications... it's just going to get tried, it's just a matter of which country it happens in. The fact that it could potentially be used by same sex couples is a total side note to how strongly this will be pulled along by the same existing demands that drive IVF currently, the potential is just too powerful. So I imagine we're just going to see eventually.
I wonder if the next step for this will be to develop techniques to modify the methylation of genes to make them compatible.
At some point you're going to want this if you're trying to pick specific genes from people or if you're doing things like making people with dozens of parents.
At some point you're going to want this if you're trying to pick specific genes from people or if you're doing things like making people with dozens of parents.
I'll just note that if modern bioethics precautionary principles were applied in the 1970s, we would probably never have gotten human IVF treatments — nobody would have ever gotten the green-light to try it on a person.
As someone who has a family because of IVF, I am very thankful that researchers were allowed to roll the dice on that one, and see that it turned out well.
As someone who has a family because of IVF, I am very thankful that researchers were allowed to roll the dice on that one, and see that it turned out well.
This puts the cart before the horse. If we have very good reason to believe we may be doing something immoral, it behooves us to be cautious.
Also, this is not a question of precaution, but a known objectively gravely immoral act. There is no risk here that we might be doing something wrong using IVF. We know with certainty that IVF is gravely immoral. That we may have obtained some outcome that is desirable does not justify the illicit means. That is, applied to your case, while it is not wrong for your family to exist per se, the means by which they were brought into existence was definitely illicit.
Also, this is not a question of precaution, but a known objectively gravely immoral act. There is no risk here that we might be doing something wrong using IVF. We know with certainty that IVF is gravely immoral. That we may have obtained some outcome that is desirable does not justify the illicit means. That is, applied to your case, while it is not wrong for your family to exist per se, the means by which they were brought into existence was definitely illicit.
I’m not sure who the “we” is in your statement, “we do know with certainty that IVF is immoral”. As evidenced by the entire rest of the thread, this opinion is hotly contested. If you believe IVF is morally wrong, please at least explain why. As it stands, you’re simply condemning families and researchers as evil and holding future research to an arbitrarily high, nebulous ethical bar with no explanation.
Let me translate for you:
"We know with certainty that IVF is gravely immoral." is essentially "I know I'm 100% right and everyone who disagrees is wrong."
Seriously, why even bother engaging with people like that who have made it exceedingly clear they are uninterested in listening. In the words of the always incisive Barney Frank, "I'd rather have a debate with a dining room table."
"We know with certainty that IVF is gravely immoral." is essentially "I know I'm 100% right and everyone who disagrees is wrong."
Seriously, why even bother engaging with people like that who have made it exceedingly clear they are uninterested in listening. In the words of the always incisive Barney Frank, "I'd rather have a debate with a dining room table."
I hesitate to put words into the mouths of others, but this sibling comment by the GP poster may explain their position
https://news.ycombinator.com/item?id=37694140
https://news.ycombinator.com/item?id=37694140
How do we know it’s gravely immoral? I’m guessing according to some interpretation of some religious text?
Otherwise, what is immoral about a couple using their own sperm and egg to conceive a child that they otherwise would not have had? I suppose you could say there are many children who need to be adopted, but that reasoning also applies to the decision to have children without IVF.
Otherwise, what is immoral about a couple using their own sperm and egg to conceive a child that they otherwise would not have had? I suppose you could say there are many children who need to be adopted, but that reasoning also applies to the decision to have children without IVF.
It's immoral in the same way abortion is immoral. If you subscribe to idea that 1) human life is sacred and 2) life starts from the moment egg is fertilized, then both abortion and IVF are immoral.
The actual reason religious people are mad at IVF is undefensible in somewhat secular society -- i.e. creating life is domain of god, thus fertilizing those embryos in the first place is bad. But with IVF there is a straw to hang on -- it's never just one egg, it's one (or two) eggs used and the rest discarded after fertilization. Which you can kinda defend as murder.
The actual reason religious people are mad at IVF is undefensible in somewhat secular society -- i.e. creating life is domain of god, thus fertilizing those embryos in the first place is bad. But with IVF there is a straw to hang on -- it's never just one egg, it's one (or two) eggs used and the rest discarded after fertilization. Which you can kinda defend as murder.
> life starts from the moment egg is fertilized
That is very much a religious idea and not something universally held. I certainly don't believe a jar of fertilized embryos is deserving of any special respect.
That is very much a religious idea and not something universally held. I certainly don't believe a jar of fertilized embryos is deserving of any special respect.
When you really dig into it, nobody actually believes this. If there was a burning building with a cooler of 10 embryos and 1 baby, and they could only save one, every single one would grab the baby.
But it's the only clean line they can draw about when human life becomes human life, so they nominally stick to it even though they don't hold by any of the logical consequences of doing so.
But it's the only clean line they can draw about when human life becomes human life, so they nominally stick to it even though they don't hold by any of the logical consequences of doing so.
>> life starts from the moment egg is fertilized
> That is very much a religious idea and not something universally held.
How so? From an entirely secular standpoint, it's the moment a distinct individual life starts (e.g. viable new organism with its own unique DNA).
> I certainly don't believe a jar of fertilized embryos is deserving of any special respect.
And that's supposed to prove what? Someone else might believe a child who has not yet met some arbitrary developmental milestone as not deserving of any special respect. And that's not hypothetical, infanticide has been common in many cultures up to and including recent times.
> That is very much a religious idea and not something universally held.
How so? From an entirely secular standpoint, it's the moment a distinct individual life starts (e.g. viable new organism with its own unique DNA).
> I certainly don't believe a jar of fertilized embryos is deserving of any special respect.
And that's supposed to prove what? Someone else might believe a child who has not yet met some arbitrary developmental milestone as not deserving of any special respect. And that's not hypothetical, infanticide has been common in many cultures up to and including recent times.
You can in theory hold such belief without being religious, but yes of course it is. The problem is -- you need to draw a line somewhere, otherwise sacred act of creation isn't sacred anymore, it's just a bunch of phenomena you can apply science to and reason about separetely. Which is of course bad.
> otherwise sacred act of creation isn't sacred anymore, it's just a bunch of phenomena you can apply science to and reason about separetely. Which is of course bad.
"Which is of course bad" - all these people thinking their personal opinions are universal, unwavering truths...
"Which is of course bad" - all these people thinking their personal opinions are universal, unwavering truths...
Or there never existed a "sacred act of creation" and its always been something we could apply science and reason to. Which is of course entirely natural.
> I’m guessing according to some interpretation of some religious text?
Alternatively, an interpretation of Aristotelianism and Platonism. There's this weird presumption that religious people mainly use texts, despite the fact that the largest denomination of the largest religion in the world, Catholicism, often ignores texts when even considering many modern moral qualms. There seems to be a real desire to reduce modern religions to some kind of magic cult, despite the fact that a lot of modern religions give great weight to secular philosophy.
In particular, the Catholic objection to IVF is rooted chiefly in Aristotle's concept of the telos, which is pretty secular. Any text in the Bible that goes along with that is just icing on the cake, not really the main objection.
Alternatively, an interpretation of Aristotelianism and Platonism. There's this weird presumption that religious people mainly use texts, despite the fact that the largest denomination of the largest religion in the world, Catholicism, often ignores texts when even considering many modern moral qualms. There seems to be a real desire to reduce modern religions to some kind of magic cult, despite the fact that a lot of modern religions give great weight to secular philosophy.
In particular, the Catholic objection to IVF is rooted chiefly in Aristotle's concept of the telos, which is pretty secular. Any text in the Bible that goes along with that is just icing on the cake, not really the main objection.
Interesting. Can you elaborate on the relevance of the telos here?
Tried responding earlier but HN is in the habit of blocking me.
Basically... The telos of sex is reproduction. To separate reproduction from sex renders sex meaningless, and thus irrational from an aristotelian perspective.
The typical objection is that sex is also for pleasure. However, Aristotle considers base pleasures like sex not worth pursuing.
Now another typical objection here is that this could mean that ivf should be pursued while we don't have sex. This is I suppose where some religion may come in since Christianity typically sees sex within marriage as a good to be pursued. Nevertheless, I've not heard any modern argument that says we should eliminate sex and sexual desire and pursue only ivf.
So basically, separating sex from reproduction renders sex meaningless and irrational.
Basically... The telos of sex is reproduction. To separate reproduction from sex renders sex meaningless, and thus irrational from an aristotelian perspective.
The typical objection is that sex is also for pleasure. However, Aristotle considers base pleasures like sex not worth pursuing.
Now another typical objection here is that this could mean that ivf should be pursued while we don't have sex. This is I suppose where some religion may come in since Christianity typically sees sex within marriage as a good to be pursued. Nevertheless, I've not heard any modern argument that says we should eliminate sex and sexual desire and pursue only ivf.
So basically, separating sex from reproduction renders sex meaningless and irrational.
>> We know with certainty that IVF is gravely immoral.
Can you expand? Are you making the claim that normal ivf is either immoral or illicit? Based on religious grounds, or actual discussable morality?
There are many ethical discussions to be had about research and potential genetic manipulation, but I'm not aware of any general "we" that believes IVF is immoral, other than orthodoxly religious. I'm eager to be enlightened otherwise!
Can you expand? Are you making the claim that normal ivf is either immoral or illicit? Based on religious grounds, or actual discussable morality?
There are many ethical discussions to be had about research and potential genetic manipulation, but I'm not aware of any general "we" that believes IVF is immoral, other than orthodoxly religious. I'm eager to be enlightened otherwise!
As an atheist, I can say that I have misgivings about it myself. At minimum, the true need for IVF is quite small compared to its demand, where it is used as a crutch by people who only came to need it after making poor decisions most of their lives.
Can you elaborate on the poor decisions, and what/who gets to evaluate or define a "true need"?
More generally - It's rare to see a truly and honestly non-religious opposition to reproductive aids, so I'd be genuinely eager to hear more!
More generally - It's rare to see a truly and honestly non-religious opposition to reproductive aids, so I'd be genuinely eager to hear more!
The biggest, would be waiting too long to attempt procreation. No one should be having kids in highschool, but if you're in your late 40s and only getting around to it at that point... waited too long.
Questionable lifestyles with all their ill health implications would be a close second.
I don't know that I could give you dozens of distinct reasons, but I bet I could fill out a top 5 pretty easy.
> and what/who gets to evaluate or define a "true need"?
Let's be objective here. If, through no fault of your own, you are sterile and childless and if technology makes it possible to effectively reverse that, then though it may not be ideal it is acceptable. Though far too late for the victims, those who were forcibly sterilized decades ago would have qualifed. Someone with some congenital issue maybe. Possibly those who have suffered peculiar accidents (more likely for men than women?).
> It's rare to see a truly and honestly non-religious opposition to reproductive aids,
If we're talking about people I care about, relatives of mine or not, I would want those children to have a true and genuine human experience. "Mommy couldn't bother to get around to making you before her ovaries shriveled up, and so Dr. Frankenbaby cooked you up in a test tube and gestated you inside GMO-gestation livestock" isn't that.
The only thing that gives me pause is that, generally speaking, I don't care about any of you. This will make it easier to think of the vast bulk of humanity as things, rather than people.
Questionable lifestyles with all their ill health implications would be a close second.
I don't know that I could give you dozens of distinct reasons, but I bet I could fill out a top 5 pretty easy.
> and what/who gets to evaluate or define a "true need"?
Let's be objective here. If, through no fault of your own, you are sterile and childless and if technology makes it possible to effectively reverse that, then though it may not be ideal it is acceptable. Though far too late for the victims, those who were forcibly sterilized decades ago would have qualifed. Someone with some congenital issue maybe. Possibly those who have suffered peculiar accidents (more likely for men than women?).
> It's rare to see a truly and honestly non-religious opposition to reproductive aids,
If we're talking about people I care about, relatives of mine or not, I would want those children to have a true and genuine human experience. "Mommy couldn't bother to get around to making you before her ovaries shriveled up, and so Dr. Frankenbaby cooked you up in a test tube and gestated you inside GMO-gestation livestock" isn't that.
The only thing that gives me pause is that, generally speaking, I don't care about any of you. This will make it easier to think of the vast bulk of humanity as things, rather than people.
> waiting too long to attempt procreation
> If, through no fault of your own, you are sterile and childless and if technology makes it possible to effectively reverse that
In the modern Western economy, it's pretty easy to find oneself not financially able to sustain a family until one is in one's early forties. I'd say people "waiting too long" are meeting your criteria.
> I would want those children to have a true and genuine human experience. "Mommy couldn't bother to get around to making you before her ovaries shriveled up, and so Dr. Frankenbaby cooked you up in a test tube and gestated you inside GMO-gestation livestock" isn't that.
For what it's worth... I gestated a bit too long and wouldn't biologically come out. Nearly died. Was "from my mother's womb untimely ripp'd," as the Bard might put it. Me and about 32% of other American births.
None of this bothers me, of course, because I don't remember any of it. I don't have any memories until about the time I was verbal. So my lack of having the true and genuine human experience of passing through a vagina into a waiting nurse or OB-GYN's arms hasn't really been, you know... An issue. For me or the other 32% of living Americans.
I'd counsel against putting hard limits on what makes for "a true and genuine human experience." This deeply unnatural technology of the Caesarean section has allowed me and millions of others a chance at life, as well as decreasing the maternal death rate drastically. If gestation in whatever a "GMO-gestation livestock" is provided even more people a chance at life... Who cares?
Such limits are also a good way to miss the awesome breadth of what the human experience is. It's a pretty wide thing. "There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy."
> If, through no fault of your own, you are sterile and childless and if technology makes it possible to effectively reverse that
In the modern Western economy, it's pretty easy to find oneself not financially able to sustain a family until one is in one's early forties. I'd say people "waiting too long" are meeting your criteria.
> I would want those children to have a true and genuine human experience. "Mommy couldn't bother to get around to making you before her ovaries shriveled up, and so Dr. Frankenbaby cooked you up in a test tube and gestated you inside GMO-gestation livestock" isn't that.
For what it's worth... I gestated a bit too long and wouldn't biologically come out. Nearly died. Was "from my mother's womb untimely ripp'd," as the Bard might put it. Me and about 32% of other American births.
None of this bothers me, of course, because I don't remember any of it. I don't have any memories until about the time I was verbal. So my lack of having the true and genuine human experience of passing through a vagina into a waiting nurse or OB-GYN's arms hasn't really been, you know... An issue. For me or the other 32% of living Americans.
I'd counsel against putting hard limits on what makes for "a true and genuine human experience." This deeply unnatural technology of the Caesarean section has allowed me and millions of others a chance at life, as well as decreasing the maternal death rate drastically. If gestation in whatever a "GMO-gestation livestock" is provided even more people a chance at life... Who cares?
Such limits are also a good way to miss the awesome breadth of what the human experience is. It's a pretty wide thing. "There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy."
> In the modern Western economy, it's pretty easy to find oneself not financially able to sustain a family until one is in one's early forties. I'd say people "waiting too long" are meeting your criteria.
In Africa, there's someone who lives on $10/month. It's not stopping them. When you talk about "being financially able to sustain a family", I get the impression you're talking about getting a purebred dog with a pedigree, because you want a pet but it can't be just any... "has to be perfect".
> So my lack of having the true and genuine human experience of passing through a vagina
No one cares about that, least of all I.
If you think it's comparable to what some people dream of though, well, I don't know what to say. Be grateful for your lack of imagination and its protective properties to the manmade horrors beyond comprehension heading our way.
In Africa, there's someone who lives on $10/month. It's not stopping them. When you talk about "being financially able to sustain a family", I get the impression you're talking about getting a purebred dog with a pedigree, because you want a pet but it can't be just any... "has to be perfect".
> So my lack of having the true and genuine human experience of passing through a vagina
No one cares about that, least of all I.
If you think it's comparable to what some people dream of though, well, I don't know what to say. Be grateful for your lack of imagination and its protective properties to the manmade horrors beyond comprehension heading our way.
> In Africa, there's someone who lives on $10/month. It's not stopping them.
Very true. How far does $10 a month go in the United States?
> No one cares about that, least of all I.
Not true. There are still people who consider cesarean section to be unnatural birth. There are still people who consider IVF to be unnatural birth. And I don't doubt that whatever "horrors" come our way, there will be people who consider being born that way an unnatural way of being until every third person they meet came into the world that way.
Very true. How far does $10 a month go in the United States?
> No one cares about that, least of all I.
Not true. There are still people who consider cesarean section to be unnatural birth. There are still people who consider IVF to be unnatural birth. And I don't doubt that whatever "horrors" come our way, there will be people who consider being born that way an unnatural way of being until every third person they meet came into the world that way.
> The biggest, would be waiting too long to attempt procreation. No one should be having kids in highschool, but if you're in your late 40s and only getting around to it at that point... waited too long.
The whole point of the article is that they are working on a technology that might obviate that particular concern.
> Questionable lifestyles with all their ill health implications would be a close second.
What does this mean? I can see an argument for wanting people to be around for their kids to grow up, but there are many risky or unhealthy behaviors that don’t harm your ability to have kids. I don’t see any particular reason to assume that having kids earlier will lead to better health outcomes (I mean there are obvious alternatives we can imagine; someone could get an advanced degree, which is correlated to a longer lifespan).
The whole point of the article is that they are working on a technology that might obviate that particular concern.
> Questionable lifestyles with all their ill health implications would be a close second.
What does this mean? I can see an argument for wanting people to be around for their kids to grow up, but there are many risky or unhealthy behaviors that don’t harm your ability to have kids. I don’t see any particular reason to assume that having kids earlier will lead to better health outcomes (I mean there are obvious alternatives we can imagine; someone could get an advanced degree, which is correlated to a longer lifespan).
> The whole point of the article is that they are working on a technology that might obviate that particular concern.
My whole point is that if you're saying "sure, you made poor life decisions, your ovaries shriveled up" but we can cook up a Frankenbaby for you, then maybe this isn't the solution to a problem, but a problem compounding on itself.
> What does this mean? I
I don't know how much more plainly I can put it. There are any number of chronic health conditions that lead to reduced fertility, those that are either caused by poor decisions, or exacerbated by them.
> but there are many risky or unhealthy behaviors that don’t harm your ability to have kids.
They might not make you 100% infertile, but they tick up whatever number you're at by some fraction of a percentage.
> I don’t see any particular reason to assume that having kids earlier will lead to better health outcomes
Having better health can make having them naturally a little more probable.
My whole point is that if you're saying "sure, you made poor life decisions, your ovaries shriveled up" but we can cook up a Frankenbaby for you, then maybe this isn't the solution to a problem, but a problem compounding on itself.
> What does this mean? I
I don't know how much more plainly I can put it. There are any number of chronic health conditions that lead to reduced fertility, those that are either caused by poor decisions, or exacerbated by them.
> but there are many risky or unhealthy behaviors that don’t harm your ability to have kids.
They might not make you 100% infertile, but they tick up whatever number you're at by some fraction of a percentage.
> I don’t see any particular reason to assume that having kids earlier will lead to better health outcomes
Having better health can make having them naturally a little more probable.
[deleted]
You mean cases like this maybe?
https://www.theguardian.com/world/2015/may/23/annegret-rauni...
At 65 the woman wanted more kids even though she had already had 13 before those 4 if i understood the article correctly. As far as i understand german doctors would not let her do an IVF but in ukraine she found a doctor. It seems they went above and beyond the usual numbers of embryos to guarantee she would get pregnant.
https://www.theguardian.com/world/2015/may/23/annegret-rauni...
At 65 the woman wanted more kids even though she had already had 13 before those 4 if i understood the article correctly. As far as i understand german doctors would not let her do an IVF but in ukraine she found a doctor. It seems they went above and beyond the usual numbers of embryos to guarantee she would get pregnant.
You want to limit access to reproductive medical technology only to those who meet your arbitrary moral criteria?
Are you certain you're an atheist?
Are you certain you're an atheist?
Well, this person hasn’t said it shouldn’t be allowed, they’ve explicitly walked it back to saying that most people don’t have a “true need” for IVF, and have made other bad lifestyle choices.
Which seems weird and judgmental, but it doesn’t necessarily have to come from a religious place.
It is hard to speculate about people’s beliefs without putting words in their mouth. But generally people can use all sorts of things (evolutionary biology, economics, whatever) to justify themselves.
Which seems weird and judgmental, but it doesn’t necessarily have to come from a religious place.
It is hard to speculate about people’s beliefs without putting words in their mouth. But generally people can use all sorts of things (evolutionary biology, economics, whatever) to justify themselves.
> Are you certain you're an atheist?
1. There is no god nor gods.
2. Jesus Christ was not a historical person, but wholly fabricated.
3. I could not find it within myself to lie about these truths, even if it forfeited my life. I would struggle to lie about it even if it forfeited the lives of loved ones.
4. Should I somehow be wrong on any of these points, then a deity that would torture me for eternity for the intellectual mistake of disbelief is in fact a devil and is my enemy which I would have wished I was clever enough to have recognized, so that I could wage war against it.
How atheist are you?
1. There is no god nor gods.
2. Jesus Christ was not a historical person, but wholly fabricated.
3. I could not find it within myself to lie about these truths, even if it forfeited my life. I would struggle to lie about it even if it forfeited the lives of loved ones.
4. Should I somehow be wrong on any of these points, then a deity that would torture me for eternity for the intellectual mistake of disbelief is in fact a devil and is my enemy which I would have wished I was clever enough to have recognized, so that I could wage war against it.
How atheist are you?
Not the OP, but you seem to be confusing atheist with having no moral norms.
Not the OP or GP either :-) but while I agree that literally everybody has internal morals, by definition; there is such a huge correlation in western society between religion and opposition to reproductive rights / aids, that I can understand the question even if not the snarky tone.
I've seen very few (not zero but close) non-religious ethical systemic discussions against reproductive aids. As I said in another comment though,I'm eager to learn!
I've seen very few (not zero but close) non-religious ethical systemic discussions against reproductive aids. As I said in another comment though,I'm eager to learn!
> people who only came to need it after making poor decisions most of their lives
Who would those be?
Who would those be?
>There is no risk here that we might be doing something wrong using IVF. We know with certainty that IVF is gravely immoral.
Sorry but... what? What about that is immoral, or... even questionable?
Sorry but... what? What about that is immoral, or... even questionable?
I can see the first attempt being immoral as we did not know how the first kids born using that method would turn out. In certain circumstances like using an IVF on older women in their menopause you could also qualify it as immoral due to higher risks to the kids. But unless you have certain religious beliefs where you cannot allow any human interference in the process, i do not see where you see the immorality of the procedure.
> We know with certainty that IVF is gravely immoral.
Why?
Why?
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Three words: Servants, Drones and Sex-Slaves
I don’t see how this is not going to end in this. What I’m less certain about is whether the Breeded will be the cannon fodder or we‘ll be…
I don’t see how this is not going to end in this. What I’m less certain about is whether the Breeded will be the cannon fodder or we‘ll be…
You can't currently create a human being via the old-fashioned method and (legally, in post places) force them to be any of those things.
There's no reason creating a human being via a new method should suddenly flip the rules and allow it.
There's no reason creating a human being via a new method should suddenly flip the rules and allow it.
Wha?! Because, religion! They are abominations!
Not really, but in history children born out of wedlock were freely discriminated against, assumed to be subhuman and criminal, and killed without repercussion.
It would be reasonable, extrapolating from (recent) history, to assume artificial humans would instantly be put in that category.
Not really, but in history children born out of wedlock were freely discriminated against, assumed to be subhuman and criminal, and killed without repercussion.
It would be reasonable, extrapolating from (recent) history, to assume artificial humans would instantly be put in that category.
None of which will happen at any sort of scale different than it happens today as long as children require a womb, 9 months in the womb, and many years of expensive care to reach an age they can become a useful servant, drone or sex slave.
We have already had these throughout history without this technology! Humans are humans no matter what they look like or how they got here and we have to treat us all equally and with respect - that’s the solution to those problems.
Japan does have a demographic problem down the road, and the only thing politicians really do care about is that taxes aren't going to get paid by themselves, you need taxpayers for that. So it's Servants from your list.
Will be very _very_ interesting to see if the tech develops enough in my lifetime to where people can send in spit samples to a medical firm, have their genome processed and then the medical company can remove any genetic predispositions to certain defects, etc... You could then also (for a hefty price), choose to have different traits embedded in your embryo - different eye colors, hair types, jawline, etc.
I'm sure we'll eventually get to the point where you can go to a medical company, throw your spit into a machine and be able to check on/off boxes for desired traits, remove negative traits, etc. etc. and have a baby ready for you under accelerated growth in weeks, not months. For added comedy, have it delivered by drone - instead of a stork delivering your child, it could be Amazon!
I'm sure we'll eventually get to the point where you can go to a medical company, throw your spit into a machine and be able to check on/off boxes for desired traits, remove negative traits, etc. etc. and have a baby ready for you under accelerated growth in weeks, not months. For added comedy, have it delivered by drone - instead of a stork delivering your child, it could be Amazon!
for anyone intrigued and/or frightened by the first half of that, here's a context-sensitive recommendation for the film Gattaca (1997) -- https://en.wikipedia.org/wiki/Gattaca
A more limited version of this is already a consumer product [1]. You can't edit the genome, but you can pick the best (for whatever your definition of best is) of the dozen or so embryos. They sequence the whole genome of all of the embryos and give you all sorts of genetic information.
[1] https://www.orchidhealth.com
[1] https://www.orchidhealth.com
"For added comedy, have it delivered by drone - instead of a stork delivering your child, it could be Amazon! "
Interesting dystopia?
But as far as I understand, the understanding of genetics is changing. Meaning there are no simple flags to set, that will enable or disable certain diseases or traits. It is way more interconnected, so your custom ordered amazon baby might have to wait a little bit longer.
Interesting dystopia?
But as far as I understand, the understanding of genetics is changing. Meaning there are no simple flags to set, that will enable or disable certain diseases or traits. It is way more interconnected, so your custom ordered amazon baby might have to wait a little bit longer.
And 50% discount if you just need a particular body part for a transplant.
Not a laughing matter, of course. The commodification of human beings is a huge problem, and one we already suffer from, a part of our cultural malaise.
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Considering Japan has a huge birth rate collapse problem, it doesn't surprise me that they are leading the way for test tube babies.
Is their birth rate a function of biological fertility problems?
It is a result of a proud tradition bound culture that is at odds with their economic reality.
Most couples are barely scraping by economically. Those who want children are faced with employers who expect their employees ass in seat 12 hours a day six days a week. Childcare is difficult.
https://www.japantimes.co.jp/news/2022/09/10/business/japan-...
Most couples are barely scraping by economically. Those who want children are faced with employers who expect their employees ass in seat 12 hours a day six days a week. Childcare is difficult.
https://www.japantimes.co.jp/news/2022/09/10/business/japan-...
To add to this, Japan is increasingly viewed as a harbinger for much of the Western world.
Previous discussion: https://news.ycombinator.com/item?id=34486824
Previous discussion: https://news.ycombinator.com/item?id=34486824
They must not care that much, since policy changes (if not cultural shift) are barely on the table. Better work-life balance is one factor that would improve the fertility rate.
Further, an attitude among Japanese women that their traditional role is bs and they want nothing to do with it. So, no marriage, no children.
It's reasonable to say, half of Japan wants their culture to continue - the men. But they need the cooperation of the women to achieve that. But they can't achieve that, without changing their culture. So deadlock.
It's reasonable to say, half of Japan wants their culture to continue - the men. But they need the cooperation of the women to achieve that. But they can't achieve that, without changing their culture. So deadlock.
No, it is not really the main cause.
But, GP's point could still be true - even if it's not the real underlying cause, it may be still enough to accelerate research in this area.
But, GP's point could still be true - even if it's not the real underlying cause, it may be still enough to accelerate research in this area.
Why would that solve anything? I don’t think that anyone has any complaints about the process of conceiving a baby naturally, it’s what happens in the 18 years following
I read that the Japanese aren't even having much recreational sex. https://www.theguardian.com/world/2013/oct/20/young-people-j...
Sex isn't recreational. But having said that, this is true of the West as well. So-called "casual sex" (again, does not exist), sleeping around, etc. is occurring at lower rates today than in the past. People are instead becoming porn-addicted shut-ins unable to have any sexual relations, let alone a healthy sexual relationship.
Is that trolling? Or did a time machine from the 1800's get invented while I wasn't looking?
No, really, almost all sex today is both those things, like it or not. Semantic struggling notwithstanding.
No, really, almost all sex today is both those things, like it or not. Semantic struggling notwithstanding.
What do you mean? A lot of people use contraception so they can have sex without procreating. Most sex today is of this type.
It's obtuse to conflate biological/gene-driven purpose with human motive.
Of course sex is (also) recreational. I’m guessing you’re coming from a religious angle, so I’ll ask: is it a sin for a married woman to have sex after menopause?
> Sex isn't recreational
It is, if done well. Otherwise I suppose it's just a chore or a duty?
It is, if done well. Otherwise I suppose it's just a chore or a duty?
Maybe there’s a competitive league but it is invite-only and they haven’t told us :(
It depends on the reasons why people do not have kids. This technique would allow gay couples to have kids for example which currently they cannot without adoption in the male case.
I wonder as well how many people do not have kids because they simply cannot find a suitable partner. Maybe this will cause a further drop in the rate of marriages and partnerships.
Of course the above solutions will only create a marginal increase but an increase none the same.
I also think that if things get bad enough the government will intervene and create institutions where these kids would get born and educated. A very brave new world scenario but if the technology allows it, i would not put it past governments to solve their problems.
I wonder as well how many people do not have kids because they simply cannot find a suitable partner. Maybe this will cause a further drop in the rate of marriages and partnerships.
Of course the above solutions will only create a marginal increase but an increase none the same.
I also think that if things get bad enough the government will intervene and create institutions where these kids would get born and educated. A very brave new world scenario but if the technology allows it, i would not put it past governments to solve their problems.
> . A very brave new world scenario but if the technology allows it, i would not put it past governments to solve their problems.
This is incredibly dangerous. From an American perspective, a government exists to serve its people. That is to say... government exists at the pleasure of its citizenry. If the government started actually making the babies (i.e., its population), then this is creating a whole other entity, one which we've not really considered before. What does it mean to be a government of the people when the government is creating the people? How can a government derive its power from the people, if the people only exist because the government created them. This would be a great inversion of the liberal democracies that have been the source of our immense progress over the last few decades.
This is incredibly dangerous. From an American perspective, a government exists to serve its people. That is to say... government exists at the pleasure of its citizenry. If the government started actually making the babies (i.e., its population), then this is creating a whole other entity, one which we've not really considered before. What does it mean to be a government of the people when the government is creating the people? How can a government derive its power from the people, if the people only exist because the government created them. This would be a great inversion of the liberal democracies that have been the source of our immense progress over the last few decades.
I did not actually think that far. It would pose the question of education with the government potentially brainwashing the new born to keep the current government in power. Is it still a democracy if people have free vote but the government mass produces electorate fodder?
And let us say if the old generation starts seeing the truth they might turn the production slightly higher to compensate. You can go even darker and speculate that the government might keep the life expectancy low genetically to avoid this kind of issue.
Obviously it presupposes that the technology will reach that stage. I hope we will never reach the industrial scale. As long as you need a woman's body to carry the child to term you will not scale it.
And let us say if the old generation starts seeing the truth they might turn the production slightly higher to compensate. You can go even darker and speculate that the government might keep the life expectancy low genetically to avoid this kind of issue.
Obviously it presupposes that the technology will reach that stage. I hope we will never reach the industrial scale. As long as you need a woman's body to carry the child to term you will not scale it.
Assumes 'the government' is effective and focussed. Mine can't get the garbage picked up on time. Not gonna worry about that one.
It could become focused if the situation justifies it. It does not have to start immediately as the dark plot described. Let us say we have a massive amount of casualties due to some accident. So as an emergency the government suggests to create a new crop of humans to replace the dead as a stopgap solution to get the country running normally again in 15 years or so. I think you could sell that to the population and companies would cooperate to achieve that goal initially.
Now again afterwards you would need to somehow conspire to continue the program to undermine your democracy. Probably this extreme case will never happen. But we could get into a sort in between zone where we still have an immoral usage of the technology but not as bad as it could be.
Note however that existing dictatorships will definitely try to use this to further their own goals.
Now again afterwards you would need to somehow conspire to continue the program to undermine your democracy. Probably this extreme case will never happen. But we could get into a sort in between zone where we still have an immoral usage of the technology but not as bad as it could be.
Note however that existing dictatorships will definitely try to use this to further their own goals.
Unlikely. It's so, so much cheaper and decades faster, to affect the minds of existing voters.
I often hear this argument, and while I (an american) often make this about my local government or even my local federal bureaucrats, the idea that the American government in particular is not effective and focused is just... completely wrong. No government in modern history has been so able to simply enforce its will via sheer force. The top brass of the American government is the epitome of effective and focussed. It really doesn't matter what the manager of your local DMV is like.
Government babies? Raised by the state, to serve the state.
Considering the gigantic problems of dwindling global resources, climate change, etc, birth rate collapse isn't a problem. It's a solution.
for the overwhelming majority the issue is raising a kid, not conceiving one. And given Japan's fairly unique aversion for kids outside marriage (I think it's like 2% compared to 40% in the US or Europe), this is almost completely cultural.
If you're facing the choice of not having kids or being delegated to married housewife a lot of women across East-Asia just choose to not want one. Understandable, really.
If you're facing the choice of not having kids or being delegated to married housewife a lot of women across East-Asia just choose to not want one. Understandable, really.
"Men in Japan do fewer hours of housework and child care than in any of the world’s richest nations. That keeps women from getting better jobs and holds back the economy."
Slightly old but relevant piece from the NYT: https://www.nytimes.com/2019/02/02/world/asia/japan-working-...
Slightly old but relevant piece from the NYT: https://www.nytimes.com/2019/02/02/world/asia/japan-working-...
Having kids outside marriage is frowned upon in general in any civilization, and marriage correlates strongly with having children. Also a contemptuous view of "housewife" shows a disregard for how demanding motherhood is (or fatherhood is, for that matter). This is a worldwide problem, save maybe for Africa, something we also see in the liberal West. People have just become comfortable and hedonistic. Having children is not comfortable. It is demanding. It requires thinking of someone other than yourself (as does marriage, also affected by this mentality). Given the choice between a nicer house and another child, many today in the West would choose the house. Consumerism, hedonistic views of sex, keeping up with the Joneses, all these contribute to reduced birth rates. Japan is clearly about as demoralized as the West, whatever the precise causes.
Clearly in your civilization anyway. One that apparently didn't include studying anthropology at any point.
Is it typical of the conservative line these days, to just repeat their antique notions and insist everybody agrees, despite evidence? It would seem so, in media anyway.
Is it typical of the conservative line these days, to just repeat their antique notions and insist everybody agrees, despite evidence? It would seem so, in media anyway.
Nothing wrong with being a married housewife. It’s callous to write with a connotation that suggests there is. In fact the best argument is that children need and should have their mother around as much as possible especially in their formative years. Children aren’t a status symbol or a car or a pet.
There is something wrong with being forced to live any kind of life you don't want. If you don't want to be a housewife then being forced to be one if you have a child is objectively awful. Japanese women have spoken, they'd rather work than have children if it means being chained to a home. Honestly even Japanese men are spoken. The gender expectations around having children aren't pleasing for them either. No one likes being forced into a life they don't want. If all it takes to avoid that is not having kids it appears many in Japan can overcome biological drives and do that.
This is from the children's point of view, and people-who-want-more-people point of view, but doesn't consider at all the person's point of view who would be making most of the sacrifices, which is the "married housewife."
Having a stay at home parent is great. Nothing wrong with a stay at home parent. Although it would be better if it was a man.
The average man has greater physical strength than the average woman, and household chores involve lots of non-automated tasks (lifting laundry baskets, etc). Plus, it is unlikely, but if there’s a burglar, men can typically put up a better fight.
The average man has greater physical strength than the average woman, and household chores involve lots of non-automated tasks (lifting laundry baskets, etc). Plus, it is unlikely, but if there’s a burglar, men can typically put up a better fight.
Some women want to be housewives, some don't. You're reading a very strange connotation into the OP's comment.
If they as a culture are no longer willing or able to reproduce, this means they have had their time under the sun. This technology is evil and will lead to immense evil. It is an abomination.
Agreed
How long until rich people start making their own clones for limb / organ / whole body transplantation?
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> IVG would render the biological clock irrelevant, by enabling women of any age to have genetically related children. That raises questions about whether there should be age limits for IVG baby-making.
Yeah, certainly can't let women breed at any age like men do.
Yeah, certainly can't let women breed at any age like men do.
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I fully support this line of work. I hope all those behaviors which lead to significant harm are outlawed and all those behaviors that lead to good outcomes are supported. Just like with every other technology in the history of humanity.
>I hope all those behaviors which lead to significant harm are outlawed and all those behaviors that lead to good outcomes are supported.
It seems very optimistic to think that humans can (a.) perform that at a germ cell level, and (b.) distinguish between moral and evolutionary goods (because they may be at odds) [0]. If the history of dog breeding is any example, quests for some perceived good lead to maladaptive features in other areas.
I’m more sanguine about possibilities in altering expression of somatic cells like what octopuses do [1].
0. https://en.wikipedia.org/wiki/Quis_custodiet_ipsos_custodes%...
1. https://news.uchicago.edu/story/octopuses-other-cephalopods-...
It seems very optimistic to think that humans can (a.) perform that at a germ cell level, and (b.) distinguish between moral and evolutionary goods (because they may be at odds) [0]. If the history of dog breeding is any example, quests for some perceived good lead to maladaptive features in other areas.
I’m more sanguine about possibilities in altering expression of somatic cells like what octopuses do [1].
0. https://en.wikipedia.org/wiki/Quis_custodiet_ipsos_custodes%...
1. https://news.uchicago.edu/story/octopuses-other-cephalopods-...
A lot of behaviors can lead to good and bad outcomes. We give guns to policemen to protect citizen. They might also misuse it. We write rules that govern these behaviors to avoid or minimize the bad outcomes.
In this scenario we already have a good idea of what people might do when given the chance if you look at science fiction.
Instead of waiting for the technology to get ready we should really think hard on which aspect of this technology we want to adopt and which ones we want to ban. For example if you can scale this technology by not requiring women wombs, should we allow the government to grow an army of clones? Would these clones have the same right as normal citizen?
We can allow individuals to have kids through this method while banning the government from misusing it (in theory).
In this scenario we already have a good idea of what people might do when given the chance if you look at science fiction.
Instead of waiting for the technology to get ready we should really think hard on which aspect of this technology we want to adopt and which ones we want to ban. For example if you can scale this technology by not requiring women wombs, should we allow the government to grow an army of clones? Would these clones have the same right as normal citizen?
We can allow individuals to have kids through this method while banning the government from misusing it (in theory).
Utterly horrifying
Something a wag wrote when the Pope allowed the rhythm method of birth control: Now you couldn't use chemistry or physics for family planning, but math was ok.
It was a joke, but it was also very true.
Was a time folks assumed fairies planted children in women's stomachs. Nowadays we know better. Lots better: now we can control the process deliberately. To claim any particular advancement in this chain of understanding is an abomination or horrifying, is a terrible temptation to update that joke.
I don't see how any human being is 'horrifying', but I fear there will be those that dehumanize some of us, and call them subhuman or make it a crime for them to be born. Resist this impulse!
It was a joke, but it was also very true.
Was a time folks assumed fairies planted children in women's stomachs. Nowadays we know better. Lots better: now we can control the process deliberately. To claim any particular advancement in this chain of understanding is an abomination or horrifying, is a terrible temptation to update that joke.
I don't see how any human being is 'horrifying', but I fear there will be those that dehumanize some of us, and call them subhuman or make it a crime for them to be born. Resist this impulse!
I reject your worldview 100% and the false equivalency between previous beliefs about childbirth and this.
It's utterly horrifying because we've seen repeatedly how corporations abuse such things.
It's utterly horrifying because we've seen repeatedly how corporations abuse such things.
"Such things".
I've done a quick google and failed to find evidence of artificial humans created from scratch. Not sure where that was going, except as hyperbole.
And it wasn't so much about childbirth as technology. Perhaps the point was hard for some to understand, so I'll elucidate.
Reproduction is a biological process that can be understood at many levels. To understand and effect change at a new level is not horrifying, not evil, not even very surprising. It's just another step in knowledge and care for human beings.
I've done a quick google and failed to find evidence of artificial humans created from scratch. Not sure where that was going, except as hyperbole.
And it wasn't so much about childbirth as technology. Perhaps the point was hard for some to understand, so I'll elucidate.
Reproduction is a biological process that can be understood at many levels. To understand and effect change at a new level is not horrifying, not evil, not even very surprising. It's just another step in knowledge and care for human beings.
Missing the forest for trees.
You are extremely naive and Short sighted.
...that it's not progressing faster.
What if in the future, the state, due to dwindling population growth creates humans from engineered eggs and sperms? The reasons to do this are obvious, no population, no growth, no profits.
Also, what if, they engineer these "artificial" humans to die preciesly when they reach a particular age? The state can then accurately predict retirement benefits, design infrastructure, distribute benefits more uniformly
Also, what if, they engineer these "artificial" humans to die preciesly when they reach a particular age? The state can then accurately predict retirement benefits, design infrastructure, distribute benefits more uniformly
Engineering people to die at a specific age is as far fetched as engineering them to live forever, so you might as well imagine the latter.
I think you could achieve the former more easily than you think. If we suppose you can gene edit to have certain characteristics. Why could they not add birth defects like heart problems and cancer? They then die from a heart attack at 30.
Of course the technology might never get there either but to me gene editing for a birth defect sounds easier than gene editing to live forever but maybe i underestimate the former.
Of course the technology might never get there either but to me gene editing for a birth defect sounds easier than gene editing to live forever but maybe i underestimate the former.
Speaking purely capitalist for sake of discussion, i wonder what would be more beneficial / ROI friendly? I suspect a steady supply of young humans would be more likely to bend to your intentions and goals than a smaller supply of humans that become more wise, bored, etc with infinite life.
Plus infinite life seems a near super power. Would they just hand it to nobodies? Seems like at that point they could produce a special few that live forever while the rest of the plebs have a largely normal life.
And heck, to extend your idea further; if it is equally difficult than perhaps you could do both, not one or the other. So make many mortals and a select few chosen royalty bloodlines that live forever. You get a population you can predictably control and forever royalty.
.. sometimes i'm glad i wasn't born 500 years later.
Plus infinite life seems a near super power. Would they just hand it to nobodies? Seems like at that point they could produce a special few that live forever while the rest of the plebs have a largely normal life.
And heck, to extend your idea further; if it is equally difficult than perhaps you could do both, not one or the other. So make many mortals and a select few chosen royalty bloodlines that live forever. You get a population you can predictably control and forever royalty.
.. sometimes i'm glad i wasn't born 500 years later.
Without knowing much of anything about either technology, I still want to speculate that we’ll probably have pretty good AI based automation before we’re creating out designer humans in bulk.
So the whole economic structure would have to be very different. Maybe AI’s will be specifically designed to serve humans, and maybe they’ll design particularly rebellious humans, as they present more novel requests.
So the whole economic structure would have to be very different. Maybe AI’s will be specifically designed to serve humans, and maybe they’ll design particularly rebellious humans, as they present more novel requests.
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I've seen things you people wouldn't believe...
It's funny to me (and I've done it too) that people mis-remember how Roy's finite life-expectancy plot worked.
It wasn't a feature; it was a bug. The company marketed it as a feature, but in reality (before Rachael, maybe) they didn't know how to build Nexus-6 with more than a four-year life expectancy. When Roy finally tracks down his creator and demands he remove it, Tyrell admits that he can't.
```
Tyrell: You were made as well as we could make you.
Roy: But not to last.
```
It's the realization that his own creator, despite all the marketing hype, isn't a god, but just another flawed mortal... that the two of them are fundamentally equal creatures in this mad universe... that pushes Roy past the edge into madness and eventual redemption, when he realizes that in the face of a universe so cold and uncaring about the life within it, it's only life that can care about life. All of it, in all its forms.
It wasn't a feature; it was a bug. The company marketed it as a feature, but in reality (before Rachael, maybe) they didn't know how to build Nexus-6 with more than a four-year life expectancy. When Roy finally tracks down his creator and demands he remove it, Tyrell admits that he can't.
```
Tyrell: You were made as well as we could make you.
Roy: But not to last.
```
It's the realization that his own creator, despite all the marketing hype, isn't a god, but just another flawed mortal... that the two of them are fundamentally equal creatures in this mad universe... that pushes Roy past the edge into madness and eventual redemption, when he realizes that in the face of a universe so cold and uncaring about the life within it, it's only life that can care about life. All of it, in all its forms.
It might be a good solution to infertility; but since infertility is not the main cause of dwindling population, artificial babies probably won't be effective in solving the general population crisis.
People who don't want to raise kids probably also wouldn't want to raise artificial kids.
If the kids are put in state's care, well, current society can't take good care of existing orphans. How are we going to handle more parent-less kids?
People who don't want to raise kids probably also wouldn't want to raise artificial kids.
If the kids are put in state's care, well, current society can't take good care of existing orphans. How are we going to handle more parent-less kids?
> If the kids are put in state's care, well, current society can't take good care of existing orphans. How are we going to handle more parent-less kids?
I have two children whom I have tried quite conscientiously to not expose to the more toxic parts of our culture. They have, to my knowledge, never watched any of the sitcoms where some significant fraction of the comedy revolves around parents and other adults complaining about having children/families. None of the standup comedians of that ilk (supposing that's still a part of their schtick). I avoid anything that talks about how "your carbon footprint will be smaller if you just don't have kids". They weren't really aware of the term "overpopulation".
Most of all, I've always talked quite fondly and genuinely of having become a father myself.
And, now, even as teenagers, they seem to look forward to the idea of becoming parents themselves one day.
I don't have a large sample size, and it's hardly scientific, but the biggest problem I think is that our culture revels in how awful parenting is. The act of believing that idea causes people to be incapable of enjoying it. I also suspect rather strongly that it is more than just some arbitrary meme that bounces around in everyone's collective heads, instead the idea itself causes people to fail to enjoy parenting and to avoid it. It becomes this self-fulfilling prophecy, should they fail to achieve lasting childlessness.
Why should such a culture deserve to even survive? Your civilization requires that people continue to reproduce, but shows nothing but contempt for the concept. It shows contempt for itself. All of the very ideals this civilization embraces and exalts seem contrary to reproduction, and no one shows any awareness that that would have to change, let alone interest in making the changes.
I have two children whom I have tried quite conscientiously to not expose to the more toxic parts of our culture. They have, to my knowledge, never watched any of the sitcoms where some significant fraction of the comedy revolves around parents and other adults complaining about having children/families. None of the standup comedians of that ilk (supposing that's still a part of their schtick). I avoid anything that talks about how "your carbon footprint will be smaller if you just don't have kids". They weren't really aware of the term "overpopulation".
Most of all, I've always talked quite fondly and genuinely of having become a father myself.
And, now, even as teenagers, they seem to look forward to the idea of becoming parents themselves one day.
I don't have a large sample size, and it's hardly scientific, but the biggest problem I think is that our culture revels in how awful parenting is. The act of believing that idea causes people to be incapable of enjoying it. I also suspect rather strongly that it is more than just some arbitrary meme that bounces around in everyone's collective heads, instead the idea itself causes people to fail to enjoy parenting and to avoid it. It becomes this self-fulfilling prophecy, should they fail to achieve lasting childlessness.
Why should such a culture deserve to even survive? Your civilization requires that people continue to reproduce, but shows nothing but contempt for the concept. It shows contempt for itself. All of the very ideals this civilization embraces and exalts seem contrary to reproduction, and no one shows any awareness that that would have to change, let alone interest in making the changes.
I'm not quite sure how your comment is a response to mine, despite you replying to me and quoting my words. I don't personally have contempt to parenthood or the act of reproduction, and I don't see how it's related to my doubt that societies would be able to take care of artificial reproduced kids, given the poor state of existing care for orphans.
You're talking about how society can't take care of existing orphans. I pointed out how it can't even take care of itself.
Also, orphans is an interesting word. This isn't Charles Dickens' London. There really aren't all that many orphans anymore. No big wars, plagues with that one exception are rather uncommon. Don't even do the thing where we steal the infants of unwed teenagers or natives anymore. When some rich people want to adopt, they usually end up having to fly halfway around the world to purchase them from warlords and conmen.
Also, orphans is an interesting word. This isn't Charles Dickens' London. There really aren't all that many orphans anymore. No big wars, plagues with that one exception are rather uncommon. Don't even do the thing where we steal the infants of unwed teenagers or natives anymore. When some rich people want to adopt, they usually end up having to fly halfway around the world to purchase them from warlords and conmen.
This is great comment, thank you
>"What if"
replace it to "when". Hopefully we can avoid it and use the tech to fix health problems for existing people
replace it to "when". Hopefully we can avoid it and use the tech to fix health problems for existing people
"In Time" (movie) would be the more likely outcome: time-to-live is transferrable currency.
But in the real world people already die at a predictable age - we are all statistics.
But in the real world people already die at a predictable age - we are all statistics.
And what if we are already the product of this process from a long forgotten empire?
>Also, what if, they engineer these "artificial" humans to die preciesly when they reach a particular age?
Pretty much a science fantasy, but what stops the population from engineering it back?
Pretty much a science fantasy, but what stops the population from engineering it back?
What stops the population from engineering fertility back in gmo seeds?
GMO crops do not have terminator genes. Enforcement is via license, not biology.
They aren't sterile (but 2nd generation crops often are less useful because it produces sibling crosses which lose the targeted benefits).
That’s the plot of Bladerunner. We bioengineer a slave class with a fixed life span and prevent them from reproducing.
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This should be banned everywhere.
It wont be. China in particular stands out as a place where this will be heavily utilized. There just arent any negative feelings towards this kind of stuff.