net.ipv4.tcp_sack=0
net.ipv4.tcp_dsack=0
net.ipv4.tcp_timestamps=0
net.ipv4.tcp_moderate_rcvbuf=0
net.ipv4.tcp_congestion_control=reno
net.core.default_qdisc=noqueue
Not to mention that `gro off` that will bump CPU usage by ~10-20% on most real world workload, Security Team would be really against turning off mitigations, and usage of `-march=native` will cause a lot of core dumps in heterogenous production environments.
[1] https://www.youtube.com/watch?v=YJB1QnEmlTs