Novavax UK results on par with mRNA vaccine while trials conducted with variants alpha/beta already circulating. due to unbinding or cross over we cannot really measure long term protection. but several studies show 2373 is better but nobody knows it
well we already have this protein based vaccine Novavax 2373 with cross immune response based on prototype developed 2.5 years ago. because it not only has full representation of spike protein (unlike mRNA taking shortcut to represent S protein) but also cleavage site which is omicron BA5 immune escape from.
However big pharma politics slowed down the approval, purpose delaying US P3 trial, introducing CMC requirement 1 month before formally submitting the application. Novavax 2373 has shown superb efficacy results since Jan 2021 UK trial and follow up study showed long term protection (titers half life 9months compared to mRNA 3months). no myocarditis risk. still FDA only approved it now half year after submission blaming the company's manufacture issue while it has been distributing hundred of millions of doses worldwide
mRNA is not vaccine. it is only genetic therapy
I am quite keen to research/trading engineer role in Singapore. I applied before and got interview for ops dev role. are they within same department or research engineer role demands higher skillsets?
i think US gov should set up H1B audit committee to audit all interview records and summon HR head to testify on hiring practice in the big corp. any fraud will be treated like financial fraud which results in prison term.
if students cheated in college and their parents are sentenced to 5 years, i think HR head should be treated as same
well put. I recently had this thought that dev is no difference from production line worker. There are only small fraction of dev sitting on top of pyramid designing blueprint and managing production line.
I am in this situation where I really hope I could apply some risk framework to help me make decision.
I recently signed an offer with a company, US bank with large python community. Now I am counter offered with more pay and promotion and internal transfer to a new team. Conventional wisdom is never accept counter offer. but this one I am giving second thought as it is not for original role but transferred to new team. I will be only one in my location and I will be building MVP for business users. it will be exposed to a lot of tech stack but it won't be scale as large as new company.
However to join a new company, there is always uncertainties like team and project. I had bad experience before. It is difficult to find it out through interview only. It seems to confirm this as I find that hiring process is a bit not taken seriously. It is greenfield project but no coding tests. There is no front end expertise in the team so I was only got asked things like "you worked with angularjs right?". Hiring manager is recruiting three altogether which he thinks will be good team.
risk is about managing uncertainties. I hope decision like this can be priced so it is easier to decide.
I see people who has CS background like to talk about performance, go deep into the subject. the common question asked how python list implemented. I reply variable array and interviewer is happy. To be honest i haven't noticed list has to resize when appending more items. probably i haven't seen real world problem.
I think there is some special code unknown to outside developer league that they can test and know you are real developer
I met one asking are you package users or know the underhood.
Your interpretation is well said. I am doing that 80% stuff. it seems to deliver a lot and feel like developers
currently I am writing very defensive codes which not addressing problem directly. I just want to get it done quickly.
I belongs to get-shit-done camp. It is so easy to check if someone has packaged a module for you. like if mongo call is blocking in tornado, i don't wrap it with coroutine. simple search i found motor/tornado redis/etc. only during debug, occasionally I jump in their codes and get idea how they do it. but that is only out of curiosity.
my work doesn't have collaboration other than users. if they want realtime feed, i do quick meteor app just a bit more complex than quick starter tutorial. I really want to break into serious development
Thank you for your advice.
The problem with my current job is I am one man team building tools for less than 20 users. I am not using Jenkins. usually I check out codes from servers and simply copied in share drive. They only saw code snippets in codepad. I think the way I talked doesn't seem like I am working in a professional team.
I have never worked in a team, doing peer coding/review. It is good to have this practice so people feel you are in their league. and usually through teamwork you get questioned and spot your area for improvement. I am kind of doing this through interview but that is really waste of opportunity this way.