I've been using a Librem 5 as a daily driver for years and before that I used a PinePhone for several years. It can work if you're willing to adjust to live with it's constraints (but then also enjoy the benefits).
Not the parent but I'll reply for myself. I have a Librem 5 as my personal phone which I take with me when I go places and use as my daily driver. I also have a Pixel running GrapheneOS with work and personal profiles for the few times I need to run an Android application but it more or less permanently stays at my desk. The Android applications I have on that phone are banking (required to use Zelle at my bank) and management applications for various devices (ex: managing settings on my bluetooth headphones). I don't need to use those often and when I do it can wait until I'm back at my desk where my GrapheneOS phone lives.