Thanks on your article. It was honest. You didn't try to blame anyone else, nor yourself. You found the market bad, and the ability to find a "killer" product harder than many "you can get rich doing this" promoters wrong.
"It is not good for man to be alone" is a phrase found in LDS ("Mormon") theology, that was spoken, purportedly, in the Garden of Eden. I am more responding to the http://news.ycombinator.com/item?id=4905386 blog post. Don't know if this Canadian IT CEO who works alone in his office is single or married. As a man married nearly 33 years, to one wife, and we being the parents of 9 children, I have been self-employed all but a handful of months (at the beginning) of those nearly 33 years. And, for the bulk of that time, I too, have long worked alone in an office.
Now I work out of my home, and the bulk of that, too, now, I am alone for.
Like the owner of that blog, I am also (now) an extrovert. But I am a man of many interests. I take some time out during my day to respond online to such things, as this, that interest me. That helps me in a small way to connect to others in somewhat similar situations.
But, being married, and having the physical intimacy that that should include helps to carry me a long way through otherwise difficult to bear circumstances.
Perhaps you could use an assistant or some other way get the cameraderie you enjoy. Or, maybe, you need to get another job like you had before. Don't know how many options are viable for you?