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maxall4

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We're All One Crisis Away from Taking Unlicensed Research Peptides

asteriskmag.com
8 points·by maxall4·mese scorso·2 comments

I led the U.S. CDC response to the 2014 Ebola epidemic

statnews.com
21 points·by maxall4·mese scorso·2 comments

The Causes of Long Covid

science.org
169 points·by maxall4·mese scorso·118 comments

Nafion

en.wikipedia.org
2 points·by maxall4·mese scorso·0 comments

Bacteria Solved the Mystery of Inheritance

worksinprogress.co
3 points·by maxall4·mese scorso·0 comments

Losing My Religion [Libertarianism]

worksinprogress.co
4 points·by maxall4·mese scorso·1 comments

Wolfram Language

wolfram.com
11 points·by maxall4·2 mesi fa·0 comments

The Left Hand of Darkness (1969)

en.wikipedia.org
5 points·by maxall4·2 mesi fa·0 comments

Dark Star (Film, 1974)

en.wikipedia.org
25 points·by maxall4·2 mesi fa·8 comments

Trump Media is merging with fusion power company TAE Technologies (2025)

techcrunch.com
3 points·by maxall4·3 mesi fa·0 comments

NIH restrictions on foreign research partnerships impacted 1 in 4 scientists

statnews.com
4 points·by maxall4·3 mesi fa·0 comments

Verquotrine – Short Story [pdf]

static1.squarespace.com
1 points·by maxall4·4 mesi fa·0 comments

An Australian man, using ChatGPT, made an mRNA vaccine to treat his dog's cancer

dawn.com
4 points·by maxall4·4 mesi fa·2 comments

Reputation (FDA's Version)

asteriskmag.com
2 points·by maxall4·6 mesi fa·0 comments

Sins of the Children

asteriskmag.com
190 points·by maxall4·6 mesi fa·88 comments

Trump calls for record $1.5T defense budget, a 50 percent jump

politico.com
16 points·by maxall4·6 mesi fa·6 comments

The Uncertain Origins of Aspirin

press.asimov.com
38 points·by maxall4·8 mesi fa·8 comments

Modern Optimizers – An Alchemist's Notes on Deep Learning

notes.kvfrans.com
46 points·by maxall4·8 mesi fa·7 comments

How A Liver Goes from a Brain Dead Donor to a Living Recipient

asimov.press
3 points·by maxall4·9 mesi fa·0 comments

The NIH ordered me to stop my 'dangerous' gain-of-function research

statnews.com
75 points·by maxall4·9 mesi fa·95 comments

comments

maxall4
·13 giorni fa·discuss
Especially an MRI which is a 3D medium —something current LLMs are very bad at.
maxall4
·16 giorni fa·discuss
Or, alternatively, it may suggest that the NSA’s classified systems are not very secure, which seems at least as possible: they may rely on requiring physical access to these systems to even attempt to penetrate them.
maxall4
·16 giorni fa·discuss
It doesn’t seem like it? Unless I am misunderstanding these Nasdaq insider trading reports: https://www.nasdaq.com/market-activity/stocks/cbrs/insider-a...
maxall4
·24 giorni fa·discuss
This is rather reminiscent of the Bogdanov affair: https://en.wikipedia.org/wiki/Bogdanov_affair
maxall4
·28 giorni fa·discuss
> We have reviewed the report and validated that the level of capability displayed there is widely available from other models (including OpenAI’s GPT-5.5), and is used every day by the defenders who keep systems safe. We will share more details over the next 24 hours.

So much for all of the rhetoric about Mythos supposedly far surpassing GPT 5.5 (edit: in cybersecurity, in particular). Of course, the AISI benchmarks also showed this, but it is amusing that Anthropic is saying it now that it is to their advantage.
maxall4
·29 giorni fa·discuss
Indeed, according to METR, Mythos only achieved an 80% success rate with 3 hour tasks. https://metr.org/time-horizons/
maxall4
·mese scorso·discuss
I’m very aware of this as well.
maxall4
·mese scorso·discuss
As someone who works in bioinformatics, and, as such, does a great deal of machine learning, this makes Fable unusable for me as well.
maxall4
·mese scorso·discuss
These safeguards are ridiculously sensitive: a prompt as simple as “ Why is an infinitely slow process reversible?” gets flagged as a ToS violation.
maxall4
·mese scorso·discuss
“The strait of Hormuz is open so long as Iran does not fire missiles at ships.”
maxall4
·mese scorso·discuss
Paper: https://www.nejm.org/doi/full/10.1056/NEJMoa2605555?query=fe...
maxall4
·mese scorso·discuss
Only an LLM could liken a first-grader to a scholar: "In a stratified society where the imperial family sat at the symbolic center, that gesture mattered. The randoseru moved, almost overnight, from battlefield to classroom, from soldier’s kit to scholar’s gear." This is an interesting topic, but this kind of AI writing gets very, very grating. Additionally, though this is somewhat unrelated, I feel like LLMs tend to argue points through gaslighting, rather than actual argumentation; they prefer to stack a bunch of tangential, or parallel, evidence and then assert that it proves their point when, in reality, it does not have any logical coherence—unless, perhaps, one reads it at 2am, in which case it might make sense.
maxall4
·2 mesi fa·discuss
Well, what else are we going to do while waiting for the bench scientists to finish collecting data?
maxall4
·2 mesi fa·discuss
Is OpenBSD actually more secure than Linux? I have not been able to find any data to support this—only some vague opinions.
maxall4
·2 mesi fa·discuss
It’s fairly overt: „The film was just starting. It was science fiction, of all things; called Dark Star.“ (pg. 111 in the mass market paperback)
maxall4
·2 mesi fa·discuss
I stumbled across a reference to Dark Star while reading the novella The State of The Art by Iain M. Banks.
maxall4
·2 mesi fa·discuss
At this scale, that kind of thing is not really a problem; you just dump all of the data you can find into the model (pre-training)1. Of course, the pre-training data influences the model, but the reinforcement learning is really what determines the model’s writing style and, in general, how it “thinks” (post-training).

1 This data is still heavily filtered/cleaned
maxall4
·3 mesi fa·discuss
> on ~2% of new prosumer signups.

I, and everyone else I have asked, see this new updated sales UI; sounds like more than 2%.
maxall4
·3 mesi fa·discuss
I have a Claude Pro tier subscription; Claude Code, as of right now, is still functional for me. If Anthropic does boot Pro-tier users off Claude Code, I will be cancelling my subscription.
maxall4
·3 mesi fa·discuss
I was part of a team researching MS at a university a while ago. It truly is an endlessly fascinating disease. Most evidence currently points to MS being caused by a combination of Epstein-Barr infection and genetic factors [0,1]. It is hypothesized that Epstein-Barr triggers autoimmunity which results in the prototypical demyelination [2].

[0]: https://www.science.org/doi/10.1126/science.abj8222

[1]: https://www.pnas.org/doi/10.1073/pnas.2424986122

[2]: https://www.nature.com/articles/s41586-022-04432-7