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mdek

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mdek
·2 anni fa·discuss
This reminds me of a very old video game "Science Sleuths"[1] I ran into as a kid, where you had to identify a blob on the beach.

[1] http://www.midnightbeach.com/hs/Sleuths.html
mdek
·2 anni fa·discuss
I agree. Give me a short, concise, unapologetic error message.

Some years ago, the Google Voice app for Android would put a message in the notification bar whenever there was even the most brief connectivity issue (which in the early days of 3G on android was frequent) starting off with "We have a problem ... <connnecting to your google voice account or something>". Considering that I used that GV number for two highly regulated activities with potential high liability, my heart would skip a beat every time a pull out my phone and see "We have a problem".
mdek
·3 anni fa·discuss
https://ijr.com/airbnb-ban-parents-conservative-youtuber-mis...
mdek
·3 anni fa·discuss
> NMS claims CLIA certification. This is the older law where labs self-certify compliance. Congress left CLIA in place alongside FDA IVD regulations to protect small pharmacists, but obviously Quest Diagnostics and LabCorp run fleets through that loophole, and most labwork is CLIA-certified, not FDA-approved.

This is highly misleading. CLIA and the associated federal regulations are the standard to which diagnostic clinical laboratories are held, not an "older" or "loophole" regulation. All laboratories in the US that provide patient results for clinical use are regulated by CLIA. There are FDA-approved test systems and "Lab-developed tests" (LDTs) that are BOTH subject to CLIA obligations, which are unbelievably complex (and in my opinion are a source of regulatory capture in laboratory medicine, but that's not directly relevant). Most high complexity lab tests are LDTs.

FDA-approved tests go through a formal FDA process such that the performing lab only has to "verify" the performance characteristics prior to patient testing. An LDT requires a much more stringent lab-level validation plan prior to patient testing. Both requiring strict ongoing quality control and quality assurance. And while the validation plan for an LDT can be self-designed, there are still strict requirements for what it most contain.

Compliance is NOT "self-certified," instead there are routine, extremely intensive compliance inspections (scheduled and unscheduled), either by a regional CLIA office, or by an organization accredited by CMS to provide such verification of compliance (such as CAP or COLA). These are not cursory inspections but a deep dive into all lab operations and personnel, equipment, maintenance and quality records, and other documentation.

I'm not a huge fan of Quest or Labcorp's presence in the field, and I don't know the specifics of NMS and this PFAS testing (CLIA compliance isn't required for research or non-clinical). If NMS has CLIA certification and they state the methodology and limitations of their LDT it's generally perfectly valid to provide the test, and the burden is generally on the downstream physician or provider to ensure the results are properly interpreted and applied.
mdek
·3 anni fa·discuss
HN thread yesterday about lead contamination of Turmeric in Bangladesh and the government's response to it: https://news.ycombinator.com/item?id=36481693
mdek
·3 anni fa·discuss
A music theory instructor from my past told us a story about his equivalent practical exam. He had to demonstrate proficiency with multiple string instruments. Instead of learning fingering for each instrument, he claimed he tuned them so they could all be played the same way. I don’t have any training in string instruments, so I’m not sure how feasible this actually is...
mdek
·3 anni fa·discuss
well, the government has definitely tried [1]

[1] https://en.wikipedia.org/wiki/FBI%E2%80%93Apple_encryption_d...
mdek
·4 anni fa·discuss
This is great, though with the usual formatting caveats of pdf printing from any browser! Firefox for Android used to have this feature up to version 60's somewhere but it was removed. I've found it useful on my android to keep an old version of firefox for limited use when I need things like pdf generation or various "unapproved" addons. Now that most of my extensions work on Firefox Nightly (with AMO), and with restored pdf functionality, there isn't much reason to keep the old version around. I'm very happy lately with firefox, both on desktop and android. I wish it would recover some market share from chrome.