AGI would be extremely helpful in navigating clashes with aliens, but taking the time to make sure it's safe is very unlikely to make a difference to whether it's ready in time. Rationalists want AGI to be built, and they're generally very excited about it, e.g. many of them work at Anthropic. They just don't want a Move Fast and Break Things pace of development.
There's also Leber congenital amaurosis, a form of blindness that now has a (very expensive) gene therapy: https://www.wgbh.org/news/2017-10-12/fda-panel-endorses-gene...