I think alphafold gets hated on too much. It won’t revolutionize things but I bet people are out there right now looking at different structures and motifs only seen on alphafold to get a better idea on how existing drugs bind and affect them. And then designing analogues and so on. Time will tell, I guess.
It’s kind of like anything in research, lots of small steps enable revolutionary breakthroughs every so often.
Not knowing anything about glyphosate, I went to the article before reading the comments. I’ll just put this here because it was clear the researchers wanted to be sure people see it. From the first paragraph of the article—>
> In 2015, the International Agency for Research on Cancer determined that glyphosate is a “probable human carcinogen” (IARC, 2015). However, the European Food Safety Authority and the Joint Food and Agriculture Organization (FAO)/World Health Organization (WHO) Meeting on Pesticide Residues (EFSA 2015, FAO/WHO 2015) determined that glyphosate is unlikely to be a carcinogen. The US EPA concluded that “available data and weight-of-evidence clearly do not support the descriptors “carcinogenic to humans,” “likely to be carcinogenic to humans,” or “inadequate information to assess carcinogenic potential” (US EPA 2017a). Controversy and concern that the rising use of glyphosate may have adverse human-health effects exist (Myers et. al., 2016).
re the CPT codes--
27486 and 27487 are for total knee revisions, not for a first-time replacement. 27486 is used if you only revise 1 component (ie the femoral side or the tibial side). 27487 is billed when both components are revised.
It’s kind of like anything in research, lots of small steps enable revolutionary breakthroughs every so often.