I would counter that by pointing out that if your aim is to achieve a certain degree of bioavailability of TCH, you'd have to smoke a larger quantity of a lower-potency product, thus exposing yourself to more of the combustion by-products than necessary.
> 2. Glucose is transported in intestines via a glucose-sodium antiporter protein. Maybe we can find a drug that blocks this and you can eat as much sugar as you want! (Turns out you’ll have uncontrolled diarrhea if you do).
It's very cool! It's the SGLT protein. It's actually a sodium-glucose co-transporter and is why gatorade is so effective! It's the perfect mix of salt, sugar, and water to take advantage of that very protein (where salt goes, water follows).
And yes there is a drug that targets these - it's the SGLT inhibitors and they're very in vogue right now. Ozempic and Mounjaro are the two big ones in the news right now. They act on the SGLT I (found only in the kidney) so that you urinate more sugar. They don't act on the SGLT 2 (only found in the gut) but other medications in that class act on both.
But congratulations and alas! You nearly invented gatorade and a multi-billion dollar diabetes and weight-loss drug. Hardly bone-headed ideas.
>But teams behave in an infinite combination of size, members, companies, and time
Slightly off topic, but I realize this is a subject I'd be interested in reading more about. Would be interested in suggestions in the same vein as Creativity, Inc. by Edwin Catmull?