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rpkoven

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[untitled]

1 points·by rpkoven·anno scorso·0 comments

Muscle-Brain Crosstalk: How Skeletal Muscle Influences Neurocognitive Function

gethealthspan.com
9 points·by rpkoven·anno scorso·0 comments

The Role of Inflammation in Exercise-Induced Reduction of Cellular Senescence

gethealthspan.com
7 points·by rpkoven·anno scorso·0 comments

[untitled]

1 points·by rpkoven·2 anni fa·0 comments

Rapamycin: Could a simple pill add years to your life?

irishexaminer.com
3 points·by rpkoven·2 anni fa·2 comments

Are the Longevity Benefits of Acarbose Rooted in Its Role on the Gut Microbiota?

gethealthspan.com
74 points·by rpkoven·3 anni fa·24 comments

[untitled]

1 points·by rpkoven·3 anni fa·0 comments

comments

rpkoven
·anno scorso·discuss
My thought is yes. There has to be neuronal death as the neuron becomes less sensitive to insulin and metabolize glucose.
rpkoven
·2 anni fa·discuss
The dynamic, wave-like model of aging aligns with the concept of quasi-programmed aging, which suggests that aging is not merely the result of accumulated damage, as proposed by the wear-and-tear model. Instead, aging reflects the unintended continuation of biological programs that were originally optimized for growth, development, and reproduction. These programs, including pathways such as mTOR, become dysregulated over time, driving aging and the onset of age-related diseases.
rpkoven
·2 anni fa·discuss
Our genes are programmed for growth, growth gets out of control, leading to our death
rpkoven
·2 anni fa·discuss
What is the cadence of giving blood to offload iron?
rpkoven
·2 anni fa·discuss
So basically I don’t have to exercise anymore?
rpkoven
·2 anni fa·discuss
No pain, no gain.

Article makes sense. No hacks.
rpkoven
·2 anni fa·discuss
Interesting that they could quantify the differences in energetic output from a mitochondrial level. I guess it’s time to start running again.
rpkoven
·2 anni fa·discuss
Vigorous exercise enhances the heart's plasticity, which refers to its ability to adapt and remodel itself in response to increased physical demands. This includes increasing the size of the heart chambers, improving the heart muscle's ability to contract, and reducing stiffness in the heart walls
rpkoven
·3 anni fa·discuss
In the first four hours following protein ingestion, the study observed a 20% higher rate of muscle protein synthesis in participants who consumed 100 grams of protein compared to those who ingested 25 grams. This difference became even more pronounced during the 4–12 hour postprandial period, where the muscle protein synthesis rates were 40% higher in the 100-gram group. Overall, this equated to a 30% larger synthetic response after consuming 100 grams of protein, as opposed to 25 grams.