LTT has a video where they tried to see how many PCIe riser cables they could string together before it stopped working.[1] They got to several meters. Maybe you could argue that it's worse inside a PC case since there's more EMI, but it seems like your PCIe riser cable would have to be very out of spec before you'd notice anything.
[1] https://www.youtube.com/watch?v=q5xvwPa3r7M