Our existence proves that life is possible.
While discovering life elsewhere would indeed be extraordinary, it is ultimately within the realm of possibility. What would be truly remarkable is making such a discovery within our lifetimes—that would be the real stroke of luck, rather than the mere fact that life exists.
I would guess that now it's quite unlikely, we might be an ant colony far, far away from others. Finding specific biota or small organisms seems like our most effective approach.