Appreciate the context, but the magnitude of effect of drugs also varies by some orders of magnitude - so it's possible/likely that the concentrations that build up over a lifetime in the body could be having some negative effect.
I work in a technical role in state gov in Australia - it feels like there will never be layoffs in my org (24k total headcount, emergency service). the problems are what you'd imagine but it's a job for life if you want it.