HackerTrans
TopNewTrendsCommentsPastAskShowJobs

carlsborg

1,882 karmajoined 12 jaar geleden
Building https://ResearchBox.ai : portable, ai-assisted streaming desktops for computational biology.

Submissions

Apocalypse Early Warning System

ews.kylemcdonald.net
261 points·by carlsborg·2 maanden geleden·129 comments

How Anthropic Teams use Claude Code [pdf]

www-cdn.anthropic.com
5 points·by carlsborg·4 maanden geleden·0 comments

AMZN Q4 2025 Results and News Release

1 points·by carlsborg·5 maanden geleden·0 comments

Filtered back-projection algorithm (X Ray Tomography)

youtube.com
2 points·by carlsborg·6 maanden geleden·0 comments

Mindstorms in Natural Language-Based Societies of Mind

arxiv.org
1 points·by carlsborg·10 maanden geleden·0 comments

comments

carlsborg
·5 dagen geleden·discuss
Correct link is https://queue.acm.org/detail.cfm?id=3819084
carlsborg
·29 dagen geleden·discuss
> AUR is just a collection of user-produced PKGBUILDs.

Is that much different from the entire pypi ecosystem, and npm, and dockerhub (people disable Selinux, --privileged turns off seccomp and apparmour, sandbox escape CVES exist)?
carlsborg
·29 dagen geleden·discuss
Pipeline is then: Cheap open source model for flagging potential LLM refusal content -> main LLM check
carlsborg
·vorige maand·discuss
Intriguing... "After months of misdiagnoses Dr Souhel Najjar, employs a test asking Susannah to draw a clock. Instead of the customary clock face, her condition led her to draw all the numbers 1 through 12 on the right side of the clock. This was the breakthrough moment; it was this clock drawing that enabled Dr Najjar to understand that the right side of Susannah’s brain was inflamed, further test revealed this inflammation was a result of anti-NMDA receptor encephalitis, initiating her path to recovery"
carlsborg
·2 maanden geleden·discuss
"Memory plus search is all you need"
carlsborg
·2 maanden geleden·discuss
Now the echo of my system prompts are bouncing round the room.

edit: Bouncing around the room is one of their hit songs. Give it a listen.
carlsborg
·3 maanden geleden·discuss
"since 2019, on the advice of the National Agency for the Safety of Medicines and Health Products, French health workers have been told not to treat fever or infections with ibuprofen." [1]

But yet in some countries pediatricians will libreally prescribe it to toddlers

[1] https://www.bmj.com/content/368/bmj.m1086

Also from [2] "In this systematic review of NSAID use during acute lower respiratory tract infections in adults, we found that the existing evidence for mortality, pleuro-pulmonary complications and rates of mechanical ventilation or organ failure is of extremely poor quality, very low certainty and should be interpreted with caution."

https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.1451...
carlsborg
·3 maanden geleden·discuss
Perhaps in due time we will see workload specific forks of Linux maintained by a team of agents
carlsborg
·4 maanden geleden·discuss
Anthropic/OpenAI could own this space. They should offer a paid service that offers a mirror with LLM scanned and sandbox-evaluated package with their next gen models. Free for individuals, orgs can subscribe to it.
carlsborg
·4 maanden geleden·discuss
> “ The agent acted like a hyperparameter optimization algorithm with some basic reasoning baked in.”

Good lens.

The crux of the auto research repo is basically one file - program.md which is a system prompt that can be summarized as “do this in a loop: improve train.py, run the training, run evals, record result. Favor simplicity”. The other files are an arbitrary ML model that is being trained.
carlsborg
·4 maanden geleden·discuss
3I/ATLAS first detected on: July 1 2025

Gamma ray burst that kept going for seven hours, fired three distinct bursts spread across an entire day: July 2 2025

just saying
carlsborg
·4 maanden geleden·discuss
This is why Montana Civil Defense survives when skynet goes rogue.
carlsborg
·4 maanden geleden·discuss
Should have funded the entire GIL-removal effort by selling carbon credits. Here's an industry waiting to happen: issue carbon credits for optimizing CPU and GPU resource usage in established libraries.
carlsborg
·4 maanden geleden·discuss
The solution is ironically, LLMs. You can construct a set of Claude skills to walk you through a code review, or understand code (anything, even course) fast.

This complexity to understanding compression will be a big market going forward.
carlsborg
·6 maanden geleden·discuss
I will add : "The Design of Design" by Fred Brooks (of The Mythical Man Month fame)
carlsborg
·6 maanden geleden·discuss
Acquired in June 2021 for $1.8 billion usd. Hurts but acquirer Naspers is a prolific tech investor, its stake in TenCent is worth > $150B usd today.
carlsborg
·7 maanden geleden·discuss
Unless you're cross platform on Windows too and then theres also a vast number of random registry settings.
carlsborg
·9 maanden geleden·discuss
People should vote on art and if you hit a threshold, you get the income.
carlsborg
·10 maanden geleden·discuss
Arguably the most familiar desktop user interface on the planet. I often wonder why complex web apps do not use this searchable start menu format.
carlsborg
·11 maanden geleden·discuss
Both are broad spectrum antivirals, but completely different mechanism.

DRACO "is a chimeric protein with one domain that binds to viral double stranded RNA (dsRNA) and a second domain that induces apoptosis when two or more DRACOs crosslink on the same dsRNA." (Ridder et al 2011). This article is about packaging mRNA for a set of 10 interferon-stimulated genes that express multiple proteins that target various stages of viral replication.