A 2.5mg/kg dose would be (extrapolating linearly) like a ~200mg dose for a 65-70kg adult. That's wayyy more that most casual users take, probably enough to induce a "k-hole" in the majority of people. Would be a curious to see results for a more realistic dose. Maybe extrapolating linearly is not appropriate however, not a pharmacology expert...
"The so-called ‘psychotically depressed’ person who tries to kill herself doesn’t do so out of quote ‘hopelessness’ or any abstract conviction that life’s assets and debits do not square. And surely not because death seems suddenly appealing. The person in whom Its invisible agony reaches a certain unendurable level will kill herself the same way a trapped person will eventually jump from the window of a burning high-rise. Make no mistake about people who leap from burning windows. Their terror of falling from a great height is still just as great as it would be for you or me standing speculatively at the same window just checking out the view; i.e. the fear of falling remains a constant. The variable here is the other terror, the fire’s flames: when the flames get close enough, falling to death becomes the slightly less terrible of two terrors. It’s not desiring the fall; it’s terror of the flames. And yet nobody down on the sidewalk, looking up and yelling ‘Don’t!’ and ‘Hang on!’, can understand the jump. Not really. You’d have to have personally been trapped and felt flames to really understand a terror way beyond falling."
I think the author takes issue with it not being intuitive, which is understandable. They do seem to acknowledge the generality is beneficial, however.
Because its the obvious outcome of the ancap principles that many on here are strongly in favour of. Company appeals to the largest market share by designing devices that work well for the majority of people. It just happens that HN readers are in the minority on this one.
Yes. The lottery is (supposed to be) uniformly random. You cannot do better than choosing a random number. If you could do so provably, that would mean the lottery wasn't fair.
It has shown to be correlated with better outcomes. It is also correlated with being healthier, being active, and eating better. As far as I understand there is no strong evidence for a causal relationship.
To be clear, if you live in the northern hemisphere, you should be taking vitamin D. It's cheap and at worst harmless. But that's not the same as saying it will improve the outcome of covid patients.
Can't wait to see the bugs! GAN's are famous for some... interesting reconstructions. And better still, nvidia will have no way to debug it since the model is essentially a black box.
Yes but physics != engineering. You really need very minimal higher math to do engineering work. As far as I know, at my school the furthest engineers go is a course in vector calculus, ODES, baby linear algebra and simple probability. None of which would be really be considered higher math. In contrast, physics needs complex variables, Pdes and most students take at least a group theory class.
Have to disagree with this. I'm a math undergrad but a good chunk of my algebra class this semester was physics students. Additionally, the author said they have a graduate degree. As far as I know (which is not very far) modern physics makes considerable use of algebraic constructions such as tensors and lie algebras, so I'd imagine the author would be familiar with these concepts, which puts them lightyears ahead of any self-taught mathematician.
I think the result would be the same no? Assuming the characters are stored in ASCII the result of a single bit flip can only possibly modify one character. Of course this assumes the program is resilient against modification in general and not just deletion (which seems to be the case).
In my completely amateur opinion, that is the one major reason why value investing is so much harder today. When Graham and later Buffett were executing this strategy to enormous success, most of a companies valuation could be traced back to it's assets -- excluding intellectual property. Now that IP is such a large part of valuations, it's much harder to execute this strategy because IP is inherently harder to valuate than tangible assets. And consequently, it's much more difficult to accurately access the difference between price and value.
> I think you're arguing on the side of "countries need monarchies because the people can't be trusted" and "printing presses allow seditious ideas to spread and must be outlawed or tightly controlled", but, again, I can't be certain.
Hard to imagine how you reached that conclusion from what I wrote.
I do somewhat agree that having the precedent of a prior bailout might encourage some potentially stupid behaviour that might not otherwise be considered. The alternative, however, is much worse (in my opinion). The point isn't to keep Morgan Stanley or Merrill Lynch or whoever in business, the point is to make sure that the rest of the country doesn't lose their entire life savings because of one recession. If the cost of economic stability is propping up a few rich people, it's probably worth it considering the alternative. Of course, I'm sure the anarcho-captilist blockchain experts might feel differently.