During my time at university studying pure mathematics I had an interesting experience of doing a challenging sheet of combinatorics problems during a vacation. Every day I attempted one question and got stuck on it. Then the next morning I woke up knowing the solution. It was a recurring thing: this happened every day for about 2 weeks until I had solved all the problems.
For me this a big eye opener about the importance of sleep and relaxed thinking to solve challenging problems.
The graph at the beginning showing the cost of sequencing over time falling faster than Moore's law stops in 2015. Would love to see how things have progressed since then. Casually googling i only saw plots up to 2021 but looks to me like progress is now slower than Moore's law since ~2015. Maybe things will change when Nanopore gets more reliable