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mulvya

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Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge

researchsquare.com
2 points·by mulvya·4 jaar geleden·0 comments

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mulvya
·3 jaar geleden·discuss
Lifetime, in theory. In practice, you can move the relationship off Upwork after 2 years.

See https://support.upwork.com/hc/en-us/articles/360043210654-Mo...
mulvya
·3 jaar geleden·discuss
This one paragraph is the sum total given for the diabetes angle:

"Rice’s nutritional quality is another growing concern. The grain is high in glucose, which contributes to diabetes and obesity, and low in iron and zinc, two important micronutrients. In South Asia the prevalence of diabetes and malnutrition can be traced to over-reliance on rice."
mulvya
·4 jaar geleden·discuss
How does that hypothesis square with this study:

No learning loss in Sweden during the pandemic: Evidence from primary school reading assessments

https://www.sciencedirect.com/science/article/pii/S088303552...
mulvya
·4 jaar geleden·discuss
Well, Ronaldo could hit a soccer ball after lights are cut.

https://www.youtube.com/watch?v=aoScYO2osb0
mulvya
·4 jaar geleden·discuss
"deal with kidney stones down the line" isn't compatible with "not good for you even small quantities"

Some of those vegetables are staples in vegetarian cuisines like here in India. There would have to be a huge epidemic of kidney stones if the latter claim was true.
mulvya
·4 jaar geleden·discuss
> oxalic acid is just not good for you even small quantities. We’ve managed to get oxalic acid out of everything we’ve domesticated

Doesn't sound right. WP has this table: https://en.wikipedia.org/wiki/Oxalic_acid#Content_in_food_it.... I see a lot of commonly eaten foods with at least a small amount of it.
mulvya
·4 jaar geleden·discuss
> There is also the case of less corruption because the indirectly elected heads of the executive aren't as beholden to special interests.

Unless these heads of the executive need private sector jobs after their tenure.
mulvya
·4 jaar geleden·discuss
Long form journalism tends to frame articles around individual narratives.

However, the article does have this:

Studies that explicitly focus on overtreatment in dentistry are rare, but a recent field experiment provides some clues about its pervasiveness. A team of researchers at ETH Zurich, a Swiss university, asked a volunteer patient with three tiny, shallow cavities to visit 180 randomly selected dentists in Zurich. The Swiss Dental Guidelines state that such minor cavities do not require fillings; rather, the dentist should monitor the decay and encourage the patient to brush regularly, which can reverse the damage. Despite this, 50 of the 180 dentists suggested unnecessary treatment. Their recommendations were incongruous: Collectively, the overzealous dentists singled out 13 different teeth for drilling; each advised one to six fillings. Similarly, in an investigation for Reader’s Digest, the writer William Ecenbarger visited 50 dentists in 28 states in the U.S. and received prescriptions ranging from a single crown to a full-mouth reconstruction, with the price tag starting at about $500 and going up to nearly $30,000.
mulvya
·4 jaar geleden·discuss
US imported even more.

https://timesofindia.indiatimes.com/business/international-b...
mulvya
·4 jaar geleden·discuss
Of course, that isn't quite true. If the result or outcome of an actvity is publicly observable or measurable, then a secondhand sense of judgement can be developed.
mulvya
·4 jaar geleden·discuss
The Q says, "entire core of it was developed and maintained by a single person"

which does not describe ffmpeg. FB was pretty active for first 4-5 years, but he wasn't the sole dev even then.
mulvya
·4 jaar geleden·discuss
> While today’s cumulative deaths is highly dependent on yesterday’s (it should theoretically never be less, for example), today’s new deaths isn’t as directly correlated to yesterday’s.

Sort of. Assuming a wave pattern, values will be close to neighbouring values and vary in an gradual manner.
mulvya
·5 jaar geleden·discuss
Obese carriers shed lot more virus, so they would be expected to have higher attack rates.

----

Exhaled aerosol increases with COVID-19 infection, age, and obesity

https://www.pnas.org/content/118/8/e2021830118

    In our observational cohort study of the exhaled breath particles of 194 healthy human subjects, and in our experimental infection study of eight nonhuman primates infected, by aerosol, with SARS-CoV-2, we found that exhaled aerosol particles vary between subjects by three orders of magnitude, with exhaled respiratory droplet number increasing with degree of COVID-19 infection and elevated BMI-years.
mulvya
·5 jaar geleden·discuss
> "selling excess stock" narrative in America

That wasn't the narrative in 2002, my first Black Friday.
mulvya
·5 jaar geleden·discuss
> there is a statement on record from politicians reacting to the suggestion with "this is not Asia, people would not stand for a lockdown"

Fauci said that in Feb 2020.

--------

    Q. How confident are you that the Chinese are doing what needs to be done?

    A. They're doing things that have completely broken the paradigm of how you respond. They have been, in a draconian way, shutting down everything. They have locked down 50 million people, including the entire 11 million-person city of Wuhan. They will not allow anyone into Beijing unless they have a 14-day quarantine. They're essentially locking people who test positive in their houses. I mean, they're doing things that are almost unheard of in the annals of public health.

    Q. Will it work?

    A. As unusual and extreme as it is, it might actually, ultimately, have an effect. There's this report that the number of new cases for the last couple of days in China has gone down. I don't put much strength in that unless I see it really start to come down and down and down. A few days of going down doesn't mean anything to me. But if it continues to go down, that might be a signal that they're having an effect of what otherwise would be extreme means.

    Q. That would never happen here, would it? Locking down 50 million people?

    A. No, not a chance. It would never happen.
--------

https://www.usatoday.com/story/opinion/2020/02/17/new-corona...
mulvya
·5 jaar geleden·discuss
Look at Table 5 on pg 19 of https://assets.publishing.service.gov.uk/government/uploads/...

For those under 50, the single-dosed have the lowest Delta CFR of 11/83009 = 0.013%; for unvaxxed it's 132/248803 = 0.053%; for double-vaxxed it's 48/85407 = 0.056%.

The lower Delta CFR for single-vaxxed vs twice vaxxed holds for those 50+ too, 1.935% vs. 2.173%.