There is some evidence that soleus push ups can induce significant insulin responses, without the need for drugs.
Soleus is the muscle below the calf and normally used when walking running and jumping
> All of the 600 muscles combined normally contribute only about 15% of the whole-body oxidative metabolism in the three hours after ingesting carbohydrate. Despite the fact that the soleus is only 1% the body weight, it is capable of raising its metabolic rate during SPU contractions to easily double, even sometimes triple, the whole-body carbohydrate oxidation.
My speculation, as with others, is that Alzheimer's disease (as well as many other slow progressing diseases) is just a metabolic disease, inline with the "type 3 diabetes" comments.
Look into supporting mitochondria health [0] and the glymphatic system [1]: good diet (with fasting), light to moderate exercise, sleep and wake at the same time each day for circadian rhythm training, reduce unnecessary stress.
Once the basics have been implemented, some supplements could help to further support cell function if needed: Longevity supplements that Dr David Sinclair takes [2], boosting cellular glutathione stores, with NACET, glycine, selenium [3]
Not to mention the social load on integrating a new person to a team. Depending on the depth, breadth and number of interactions with other individuals, this causes others to have to also get up to speed on the new person's strengths, weakness, quirks, etc.