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JR1427

598 karmajoined 3 lata temu
Dev living in an old UK university city.

comments

JR1427
·3 dni temu·discuss
I used to read it every week, and always liked the fact they stated their biases upfront - "This newspaper believes XYZ".

Now I just live under a rock, and don't read any news.
JR1427
·3 dni temu·discuss
Totally agree. Programming is not art. Does my company pay thousands of engineers to make art? I think not!

We're paid to solve a problem that the customer has.
JR1427
·4 dni temu·discuss
I used to use that a lot, but now would favour bowline, for ease of tying and untying. Less beginner-friendly, though.
JR1427
·4 dni temu·discuss
Knowing common knots is not just useful because they are handy, but they also represent a common toolkit - when sailing with someone, if I see they tie a certain thing with a specific knot, I can do likewise. When I see a knot I recognise, I immediately know how to untie and re-tie it.
JR1427
·4 dni temu·discuss
Depends what you're doing.

My favourite knot is the bowline. Non-slip loop, very strong, easy to tie, easy to undo. Can be used for tying two ropes together, ropes to things.

Other useful ones (especially for sailing)

* Clove hitch * Reef knot * Rolling hitch * Sheet bend
JR1427
·12 dni temu·discuss
All my university (Oxford, UK) exams were in-person and had written. I had 6 exams over 6 days in 2012, in which my entire undergraduate degree was examined.

It's not easy, but I think that method is just as good (or bad) now as it was then.
JR1427
·12 dni temu·discuss
If hair greying was mostly caused by UV damage, I would expect that the pattern of greying would be even, and begin on the top of the head.

In contrast (based on my own unscientific observations!) greying typically begins in small areas, and often on the temples - not what I'd expect if caused by UV damage.
JR1427
·12 dni temu·discuss
When most people think of age-related hair greying (which you referenced in your original post), they think of the phenomenon whereby hair follicles stop producing pigments that colour hair.

This is distinct from UV bleaching of the pigments in the hair.
JR1427
·12 dni temu·discuss
After a quick skim, that article seems to be talking about something other than typical age-related greying. More photobleaching.
JR1427
·12 dni temu·discuss
I've not heard that grey hair is sun damage.

Do you have any sources for that?
JR1427
·30 dni temu·discuss
I really recommend reading "Ravens in Winter" by Bernd Heinrich https://jake-reich.co.uk/blog/17
JR1427
·w zeszłym miesiącu·discuss
(forgot to say I'm a former post-doc in Cell Biology)
JR1427
·w zeszłym miesiącu·discuss
Images like this show how specifically the antibody binds to the antigen. Generally, the ideal is to have very specific binding. As such, this type of image (Western blot) would only have single bands in any vertical lane. Any other bands show that the antibody is binding to other molecules.

The evidence of painting out the background is likely someone cleaning up other bands, where the antibody has bound to something other than the intended target. So, they are making out the antibody is better than it actually is.

Copy-pasted bands could be evidence of attempting to make a weak band look stronger, or even adding a band where one didn't exist - potentially the entire blot is fabricated.

Either way, like someone else said, this is like fabricating parts of a data sheet.

It doesn't excuse it, but like someone else said, scientists would never just trust an antibody they bought. They'd do their own tests. Labs will also share notes amongst each other, along the lines of "that antibody is bad, and also strongly binds XYZ. You should try this other one instead".
JR1427
·w zeszłym miesiącu·discuss
Travel, adventure, camaraderie, to name a few.

At university I started down the path of joining the infantry as an officer. At first it was great fun - getting paid to go camping on weekends away from university. But when the political side began being pressed home more and more, it didn't sit well with my beliefs. Oh, and I met my now wife at that time, and didn't want to go disappearing off.

I ended up getting a PhD, doing academia for a couple of years, then moving in to industry. Some of it was fun, but the itch for proper adventure has never really left.

Now with a young daughter, we have mild family adventures, which are fun in their own right, but I do hope to have bigger adventures one day. Hopefully with my wife and daughter.
JR1427
·w zeszłym miesiącu·discuss
My home wifi doesn't reach my side the bed from the router downstairs.

Best way to prevent doomscrolling.
JR1427
·3 miesiące temu·discuss
A central package cooldown is not really any different to individual cooldowns.

The main reason for the cooldown is so security companies can find the issues, not that unwitting victims will find them.

One problem of the central cooldown is that it restricts the choice to be able to consume a package immediately, and some people might think that a problem.
JR1427
·3 miesiące temu·discuss
I have cut myself once, and only once with a sharp knife. I was about 7 years old, and my grandfather gave me a new (sharp!) Swiss army knife.
JR1427
·3 miesiące temu·discuss
> It's basically rabid conservation and tragedy of the commons writ large

How is this like "tragedy of the commons"?
JR1427
·3 miesiące temu·discuss
Call it what you want, but a new life stage begins when we have serious responsibility for another human.

For some this comes early, like a "child" looking after a sick parent. For others (like me) this comes with having children.

My wife and I look back on the years we thought we were adults, because we lived on our own, had jobs and a cat, and chuckle to ourselves at how grown up we thought we were. This type of pretending to be an adult we call "adulting".
JR1427
·4 miesiące temu·discuss
AWS Graviton and Microsoft Cobalt are arm-based.