> A group of researchers mostly based at Columbia University are testing whether valacyclovir, an antiviral used against HSV1, can slow down cognitive decline in people with early stage Alzheimer’s. Between 2018 and 2024, the researchers recruited 120 patients and treated half with the antiviral.
Outsider view: while I'm excited we're making progress, I can't shake a feeling of sadness that the best we could manage was a study this small, started 7 years ago. If it's as pivotal as the article suggests, one would hope we could get more than 60 people in the experimental arm (IIUC this antiviral is widely prescribed, well-tolerated, and off-patent). Nonetheless, excited to see the outcome
I have similar issues with sleeping hot. I bought a similar open-knit weighted blanket from yaasa this year and really like it.
Having a small fan blowing air over me also helps quite a bit (the Vornado 5303DC has a remote and can adjust in 1% increments which is very nice for adjusting temp a bit during the night).
I share your concerns about the corrupting influence of money (and the importance of this space), but wanted to point out that Anthropic announced two relevant things last week regarding corporate governance:
First, that it has arranged to be controlled by a Long-Term Benefit Trust: "an independent body of five financially disinterested members with an authority to select and remove a portion of our Board that will grow over time (ultimately, a majority of our Board)". (https://www.anthropic.com/index/the-long-term-benefit-trust)
Outsider view: while I'm excited we're making progress, I can't shake a feeling of sadness that the best we could manage was a study this small, started 7 years ago. If it's as pivotal as the article suggests, one would hope we could get more than 60 people in the experimental arm (IIUC this antiviral is widely prescribed, well-tolerated, and off-patent). Nonetheless, excited to see the outcome