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kevlened

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1 points·by kevlened·3 miesiące temu·0 comments

Creators of Tailwind laid off 75% of their engineering team

github.com
1,457 points·by kevlened·6 miesięcy temu·840 comments

SimpleFold: Folding proteins is simpler than you think

github.com
471 points·by kevlened·10 miesięcy temu·132 comments

comments

kevlened
·8 dni temu·discuss
That's quite a complement to AI
kevlened
·17 dni temu·discuss
We have already seen selection pressure results in Candida auris

https://journals.asm.org/doi/10.1128/mbio.01397-19 (2019)

https://radiolab.org/podcast/fungus-amungus (2020)
kevlened
·17 dni temu·discuss
It can be airborne, lives on sanitized surfaces for up to 10 weeks, and may take 3 years for symptoms to appear.

Still, it is more concerning for cats than humans.
kevlened
·w zeszłym miesiącu·discuss
From my experience, the team that's the closest to open-source pixel-perfect Word support is https://github.com/superdoc-dev/superdoc (unaffiliated)
kevlened
·w zeszłym miesiącu·discuss
One argument may be that ownership is the last role for a human in a business. The firm exists to show ownership of an AI and provides a mechanism for managing its proceeds.
kevlened
·3 miesiące temu·discuss
Derek Muller of Veritasium has a presentation on why the promises of a revolution in education are never fulfilled. [0]

His hottest take is we're already close to the optimal process for learning, so technology isn't going to improve it. Learning takes work, and no technology can do the work for you.

[0] https://www.youtube.com/watch?v=0xS68sl2D70
kevlened
·3 miesiące temu·discuss
Nanoclaw uses the official claude agent sdk, so it should be unaffected.
kevlened
·3 miesiące temu·discuss
For those looking for an MIT alternative, there's an embeddable solution which uses PDFium (Apache) compiled to wasm instead of MuPDF (AGPL): https://www.embedpdf.com/

There's a hosted version for quick edits: https://app.embedpdf.com/

Discussion from several months ago: https://news.ycombinator.com/item?id=44901683

Neither fully handles XFA, but that's a perennial struggle.
kevlened
·4 miesiące temu·discuss
> A recent study from Stanford

Source?
kevlened
·5 miesięcy temu·discuss
Even without prior knowledge, seeing others safely navigate the same section will lower your estimated risk.
kevlened
·5 miesięcy temu·discuss
> Musk miscalculated on 1) cost reduction in LIDAR

Given that Musk has a history of driving lower costs, it's unlikely he overestimated the long-term cost floor. He just thought we were close to self-driving in 2014.

Another factor is Andrej Karpathy, who was the primary architect for the vision-only approach. Musk wanted fewer parts, and Karpathy believed he could deliver that. Karpathy is still an advocate of vision-only.
kevlened
·5 miesięcy temu·discuss
> They also published the report here: https://pub-fee113bb711e441db5c353d2d31abbb3.r2.dev/VTT_CR_0...

That's the same link. Is there a way to attest that this is an official VTT report?
kevlened
·5 miesięcy temu·discuss
> Oxfmt got it, and then won.

This doesn't align with the data.

  - 650k npm downloads for oxfmt this week [0]
  - 4.3m npm downloads for biome this week [1]

  - 19.1k gh stars for oxfmt [2]
  - 23.7k gh stars for biome [3]
  - gap widening in favor of biome [4]

  [0] https://www.npmjs.com/package/oxfmt
  [1] https://www.npmjs.com/package/@biomejs/biome
  [2] https://github.com/oxc-project/oxc
  [3] https://github.com/biomejs/biome
  [4] https://www.star-history.com/#oxc-project/oxc&biomejs/biome&type=date&legend=top-left
kevlened
·5 miesięcy temu·discuss
There's an active proposal for rendering html in canvas to control styling. Text rendering and accessibility are main focuses for the proposal.

https://github.com/WICG/html-in-canvas
kevlened
·5 miesięcy temu·discuss
He's changed wild-type planarians to grow the heads of other species. It reverts after a few weeks, because the system has error-correcting mechanisms, but the DNA of these worms is unchanged.

He once compared tinkering with DNA as pulling out a soldering iron to fix a software bug.

In the case of morphology, DNA may not be the best level of abstraction. It's certainly possible, just as one can use chemistry for social problems, but for some problems, affecting cell-to-cell communication may be a more direct path.
kevlened
·6 miesięcy temu·discuss
More details:

https://github.com/tailwindlabs/tailwindcss/discussions/1467...

https://x.com/adamwathan/status/2008909129591443925

https://adams-morning-walk.transistor.fm/episodes/we-had-six...
kevlened
·7 miesięcy temu·discuss
> The only thing I see in the QC space, are QC stocks and funding paying for the employment of scientific experimentation

Then invest accordingly, and later reinvest your winnings in a different direction.
kevlened
·7 miesięcy temu·discuss
I've had to switch from SSE to WebSockets to navigate a corporate network (the entire SSE would have to close before the user received any of the response).

Then we ran into a network where WebSockets were blocked, so we switched to streaming http.

No trouble with streaming http using a standard content-type yet.
kevlened
·7 miesięcy temu·discuss
> Find me a “lights out” factory. They don’t exist.

"Inside China's 'dark factories' where robots run the production lines" https://www.youtube.com/watch?v=ftY-MH5mdbw

"China’s Dark Factories: So Automated, They Don't Need Lights" https://www.youtube.com/watch?v=MCBdcNA_FsI
kevlened
·7 miesięcy temu·discuss
Standard .env is unencrypted, while a dotenvx .env file has plaintext keys and encrypted values. Anyone with access to the repo would also need the DOTENVX_PRIVATE_KEY variable to decrypt the env file.

One key deployed to your hosts means adding new secrets doesn't take operations effort. Also, the process uses a public/private key pair, so adding a new variable doesn't expose existing variables.