I've come across plenty of evidence in the literature but there are lot of variables that can prevent any positive effects from taking place. If you're taking probiotic supplements in isolation and the rest of your diet is suboptimal in terms of bacteria-friendly nutrients, it's unlikely that you'll get results. It could be the case that many people are throwing money away if they're taking probiotic supplements without addressing their diet and lifestyle.
There's so much variety between people, one formulation for one person might work well for one person but have negative effects on another even if they have a supportive diet and lifestyle. People might simply have to trial multiple formulas that have the right mix of strains before they find one that works for them.
Prebiotic foods seem to have more consistent results on gut health, according to some studies.
Weird question perhaps, some research suggests that bacteria source nutrients from the cell lining in the gut if there is an absence of sufficient nutrients from the food coming into the digestive system. (example: https://www.cell.com/cell/fulltext/S0092-8674(16)31464-7)
That made me wonder what the triggers might be, since the studies see the corroding effect appear in diets deficient in polyphenols/insoluble fibres. At what interval do microbes need nutrients and is simply eating a highly-processed snack that has nothing much to offer bacteria in the gut a possible trigger in itself?
What was your diet like when you were taking them? It's been observed in some studies that delivered mixed results that responders had better diets (i.e. more bacteria friendly components in the diet such as indigestible carbs from vegetables/legumes/fruit etc) whereas non-responders had weaker diets in terms of providing the gut microbes nutrients.
Alcohol consumption was pretty common in the NBA, with some even drinking during halftime. Some of the biggest stars of the league in the past decades drank a lot of alcohol, though much less now with more stringent policies in place. There are players that led the league in scoring despite drinking well into the night all the time. Lebron James is a famous wine drinker. He drinks every day and his longetivity and conditioning is unmatched, but he may be from a different planet.
These were some random facts from an NBA fan who doesn't drink.
I agree, if you had to get a team together with the sole purpose of crushing people's spirit and grinding people down with opinions while appearing to be somewhat wellmeaning, the guardian would be a stellar example of that.
Compassion/self love is what made me change my lifestyle and overcome excuses. If you have compassion for the work that your organs are doing, you are going to be more motivated to do the things that keep those organs healthy, while doing less of the things that damage them. One day I heard someone talking about how the heart has to work harder pumping blood around if you sit all day. I couldn't shake the thought, so eventually I started moving more and adopted a cold shower routine despite hating the cold. I started giving a shit about my cardiovascular health as a result of compassion. I didn't have to crack the whip either, making lifestyle adjustments just felt like the right thing to do.
Compassion is not about making people feel better for not taking care of their situation/body/work/goals/life/relationships, it's about acting with a level of care for the things that matter most.
In the UK over 300 hundred thousand adverse events have been reported to the yellow card system, with over a 1000 deaths. I've heard that VAERS underreports because medical professionals don't have the time to make the submissions (I don't really know if that's true or not). It's impossible to confirm what the precise risks are and whether those reporting systems are over- or understating the real picture, but it's irresponsible, I think, to handwave about risks to someone who clearly had a bad response.
I know someone who had both the myocarditis as well as a severe allergic reaction, which could have been fatal if she hadn't received benadryl in time. After that, she was advised by her doctor to not get the 2nd shot. But because the social pressure being placed on people is so high, she is still minded to get the 2nd shot even when her own doctor advises against it. I don't think medical decisions should be swayed by peer pressure from people on the internet, or an employer.
I don't understand why this batch of vaccines is being compared to vaccines for other diseases as if they are the same thing. Other vaccines are generally mandated for children with extremely high efficacy, have an extremely low chance of adverse events, prevent community spread perfectly or almost perfectly, have an exactly known quantity of doses required and are deployed as prevention (not in the midst of a pandemic). Importantly, they treat diseases that cause extremely bad outcomes in children at very high rates. This current generation of covid vaccines is more like a drug that works well for some and not so for others, doesn't prevent transmission, aims at moving target, requires an unknown amount of doses, only modestly discourages continued spread and represents one of many ways for society to treat, tackle and prevent the disease. This is a disease that is trending downwards in its mortality rate, while being of fairly low risk for the majority of the population, with the lowest risk found for young people. The diseases we mandate children to get vaccinated for are not declining in their disastrous health effects as far as I know. The risk of adverse events from the current set of covid vaccines is lowish but not particularly low. All that doesn't make the vaccines we have for covid any less important, but the comparison really does not wash and is a highly dubious way of engaging around the topic of body sovereignty.
There are a small group of people out there who are scared to death to take this vaccine because they genuinely think it will do harm to them. They are being asked to override their own alarms by people who do not share the fear because they don't have the same alarm bells going off. I know only a few of these people and they all have a ton of prior negative experiences with the medical system that would have left me feeling much the same way if I had shared their experiences personally. There are people that have been put in a 'do as you are told' situations and have received medical interventions that have done them great harm. Now they are being hounded and once again are being told to do as they are told, while fearing for their own health. A lot of people are willing to sweep aside their concerns as if they are asocial, ignorant, stupid, irresponsible and part to blame for the scale of the epidemic. People who feel out of control want to blame others so very badly, concentrating culpability in the hands of a group of bad actors, and it results in completely warped thinking with a tendency to dehumanise. And people can pick this up in others and it only increases their skepticism. They fear people operating in a blinkered, blame-seeking authoritarian way, and they see that as danger.
Though I encourage vaccination and have repeatedly tried to talk people who fear it off the ledge, I totally understand where the dictatorship and corruption logic is coming from. It doesn't take a hard-core cynic to raise an eye-brow when a drug company CEO proclaims that we'll all be needing many repeated doses of their product for years to come, while a leading political figure with immediate ties to the biotech industry wants to encourage countries to mandate the use of their products. If you had told me 2 years ago that society would control, monitor, demonise and divide people on the basis of having or having not received a recent government sanctioned medical treatment, I would have probably called you a hysterical conspiracy nut.
Am I an odd case? Nowadays all my side-project code is to scratch an itch, fix a problem or create a solution I want to use that doesn't exist yet. I'm not motivated by the tech itself and the money is not a primary driver either.
The data on Time Restricting Eating shows that you most probably will experience benefits even with a feeding window as wide as 12 hrs. I do 10hrs and it's been very good for me.