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rpkoven

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[untitled]

1 points·by rpkoven·w zeszłym roku·0 comments

Muscle-Brain Crosstalk: How Skeletal Muscle Influences Neurocognitive Function

gethealthspan.com
9 points·by rpkoven·w zeszłym roku·0 comments

The Role of Inflammation in Exercise-Induced Reduction of Cellular Senescence

gethealthspan.com
7 points·by rpkoven·w zeszłym roku·0 comments

[untitled]

1 points·by rpkoven·2 lata temu·0 comments

Rapamycin: Could a simple pill add years to your life?

irishexaminer.com
3 points·by rpkoven·2 lata temu·2 comments

Are the Longevity Benefits of Acarbose Rooted in Its Role on the Gut Microbiota?

gethealthspan.com
74 points·by rpkoven·3 lata temu·24 comments

[untitled]

1 points·by rpkoven·3 lata temu·0 comments

comments

rpkoven
·w zeszłym roku·discuss
My thought is yes. There has to be neuronal death as the neuron becomes less sensitive to insulin and metabolize glucose.
rpkoven
·2 lata temu·discuss
The dynamic, wave-like model of aging aligns with the concept of quasi-programmed aging, which suggests that aging is not merely the result of accumulated damage, as proposed by the wear-and-tear model. Instead, aging reflects the unintended continuation of biological programs that were originally optimized for growth, development, and reproduction. These programs, including pathways such as mTOR, become dysregulated over time, driving aging and the onset of age-related diseases.
rpkoven
·2 lata temu·discuss
Our genes are programmed for growth, growth gets out of control, leading to our death
rpkoven
·2 lata temu·discuss
What is the cadence of giving blood to offload iron?
rpkoven
·2 lata temu·discuss
So basically I don’t have to exercise anymore?
rpkoven
·2 lata temu·discuss
No pain, no gain.

Article makes sense. No hacks.
rpkoven
·2 lata temu·discuss
Interesting that they could quantify the differences in energetic output from a mitochondrial level. I guess it’s time to start running again.
rpkoven
·2 lata temu·discuss
Vigorous exercise enhances the heart's plasticity, which refers to its ability to adapt and remodel itself in response to increased physical demands. This includes increasing the size of the heart chambers, improving the heart muscle's ability to contract, and reducing stiffness in the heart walls
rpkoven
·3 lata temu·discuss
In the first four hours following protein ingestion, the study observed a 20% higher rate of muscle protein synthesis in participants who consumed 100 grams of protein compared to those who ingested 25 grams. This difference became even more pronounced during the 4–12 hour postprandial period, where the muscle protein synthesis rates were 40% higher in the 100-gram group. Overall, this equated to a 30% larger synthetic response after consuming 100 grams of protein, as opposed to 25 grams.