While the order of the walls in Super Hexagon is random, each level has a predetermined set of walls. Once you identify which wall pattern is coming you know exactly the maneuver needed to traverse it.
This makes Super Hexagon more a game of quick pattern recognition than reaction time.
When I play it I am generally focused at the edges of the screen to quickly identify the next pattern and only using my peripheral vision to maneuver around the walls in the center.