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treprinum

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treprinum
·2 lata temu·discuss
Isn't thiamine tissue deficiency at the bottom of dysautonomia? Potentially leading to Alzheimer, MS, ALS over long periods of time if untreated depending on one's genetics and the way their body tries to adapt to it? I understand nobody tracks this over 30 years though. I think it's low-risk to try to address long-term tissue B1/B2/B3 deficiencies first and see if it helps.

"The initial symptoms of thiamine deficiency beriberi are those of dysautonomia [1], a broad term that describes any disease or malfunction of the autonomic nervous system. This includes postural orthostatic tachycardia syndrome (POTS), inappropriate sinus tachycardia (IST), vasovagal syncope, mitral valve prolapse dysautonomia, pure autonomic failure, neurocardiogenic syncope (NCS), neurally mediated hypotension (NMH), autonomic instability and a number of lesser-known disorders such as cerebral salt-wasting syndrome. Dysautonomia is associated with Lyme disease, primary biliary cirrhosis, multiple system atrophy (Shy–Drager syndrome) Ehlers–Danlos syndrome and Marfan syndrome for reasons that are not fully understood [2]. It has been hypothesized that the association of dysautonomia with so many different diagnoses is because a common form of dysautonomia originates from high calorie malnutrition. This leads to loss of oxidative efficiency (pseudo hypoxia) and subsequent disorganization of ANS controls that are mediated through the limbic system and brainstem."
treprinum
·3 lata temu·discuss
https://old.reddit.com/r/programming/comments/3ji148/jetbrai...

https://old.reddit.com/r/programming/comments/3jjb2f/if_you_...

Their CEO literally used the words "we have listened" after the uproar.

https://blog.jetbrains.com/blog/2015/09/03/pr_030915/

https://blog.jetbrains.com/blog/2015/09/18/final-update-on-t...
treprinum
·3 lata temu·discuss
The JetBrains experience?
treprinum
·3 lata temu·discuss
Yeah, Automobilista 2 or Flight Simulator 2020 are a joy on Reverb G2. Though I must say I was surprised how tiny Monaco felt which is probably a question of FOV.
treprinum
·3 lata temu·discuss
PinePhone + PineKeyboard might be what you are longing for. Maybe even Planet Computers Gemini.
treprinum
·3 lata temu·discuss
For example, tutorial on how to fix/replace things, how do things work internally, playing chess, demo surgery etc.
treprinum
·3 lata temu·discuss
Not a single AR functionality was demoed; all that was shown was a 2D overlay on top of real-world view. No 3D computer vision segmenting objects on the screen, no placing 3D objects on real objects etc. It felt less capable than Hololens a few years back.