Probiotic that produces lactase enzymes directly in gut(bactose.com)
bactose.com
Probiotic that produces lactase enzymes directly in gut
https://bactose.com/
31 comments
Hi Mataug,
Thanks for posting, we are super small so we notice these things, haha. LA does produce lactase naturally, ours produces about 60% more than other LA strains, and also adheres to the intestinal lining really well, which is why it can last so long.
We have a moneyback guarantee, so if you want to order it on subscription and use the discount code on the site, you can get it pretty cheap, then also if do not like it send us an email to get a refund.
Let me know any other questions or requests.
Thanks for posting, we are super small so we notice these things, haha. LA does produce lactase naturally, ours produces about 60% more than other LA strains, and also adheres to the intestinal lining really well, which is why it can last so long.
We have a moneyback guarantee, so if you want to order it on subscription and use the discount code on the site, you can get it pretty cheap, then also if do not like it send us an email to get a refund.
Let me know any other questions or requests.
$40 a month, and you still have to take 3 a day for a week. Nah. I’ve been dealing with carrying pills around for decades, it’s not that onerous. The price of lactase has come down too, used to be like $0.50 per pill, but I still don’t think I ever took 80 of them a month.
Plus it makes me more mindful of what I’m eating generally, and also encourages me to try and even make new stuff, especially drinks - kombucha, kvass, kefir water, oat milk, homemade syrups for soda, etc.
Plus it makes me more mindful of what I’m eating generally, and also encourages me to try and even make new stuff, especially drinks - kombucha, kvass, kefir water, oat milk, homemade syrups for soda, etc.
Yea, you can get 180 pills from CostCo for $18 ($0.10 / pill). These seem wildly over priced considering that it defines "long-lasting" as 1 month, meh.
For a year this is $40 * 12 = $480.
Or I could get 180 pills from CostCo (and you could probably source these cheaper) for $18, even if I ate dairy at every meal 365 * 3 = 1095, I would only need 1095 / 180 = 6.08 (round up to 7) boxes of Fast-Acting Lactase which is only 7 * $18 = $126.
This is 4 times the price and for 1 week each month I need to remember to take 3 pills a day. The value prop just doesn't add up, it's not hard to source or have lactase pills on hand.
https://www.costco.com/kirkland-signature-fast-acting-lactas...
For a year this is $40 * 12 = $480.
Or I could get 180 pills from CostCo (and you could probably source these cheaper) for $18, even if I ate dairy at every meal 365 * 3 = 1095, I would only need 1095 / 180 = 6.08 (round up to 7) boxes of Fast-Acting Lactase which is only 7 * $18 = $126.
This is 4 times the price and for 1 week each month I need to remember to take 3 pills a day. The value prop just doesn't add up, it's not hard to source or have lactase pills on hand.
https://www.costco.com/kirkland-signature-fast-acting-lactas...
Check out my comment above, but I just wanted to say I am a costco whore, everything from the snacks in my pantry and freezer, to my tv to furniture is costco derived. If you are in Austin, we should go hit up a costco together, I am serius.
> defines “long-lasting” as 1 month
Where’s this? You take a pill with each serving of dairy. I usually carry a strip of 3 or 6 individually packaged pills if I’m out for the day. Each pouch has an expiration date on it, and that’s at least a couple of years, so I leave stashes in the car, camera bag, friends’ houses, wherever.
Even taking 3 or 4 on some days, you’re still right, the cost isn’t much of an issue.
Where’s this? You take a pill with each serving of dairy. I usually carry a strip of 3 or 6 individually packaged pills if I’m out for the day. Each pouch has an expiration date on it, and that’s at least a couple of years, so I leave stashes in the car, camera bag, friends’ houses, wherever.
Even taking 3 or 4 on some days, you’re still right, the cost isn’t much of an issue.
Apologies if my original comment wasn't clear. Fast-acting Lactase is something you take with every serving of dairy. The Bactose product that this post is about says the following
"Long lasting effects Bactose™ will continue to thrive digesting lactose for the whole month, individual results may vary."
I was trying to say that the Bactose product's "long-lasting" claim falls a bit flat when you realize it only lasts a month. If I could take some pills for a week and then be set for 6-months or a year, yea, I might drop $40 on it.
"Long lasting effects Bactose™ will continue to thrive digesting lactose for the whole month, individual results may vary."
I was trying to say that the Bactose product's "long-lasting" claim falls a bit flat when you realize it only lasts a month. If I could take some pills for a week and then be set for 6-months or a year, yea, I might drop $40 on it.
Our product is about convenience, if you are happy with your current situation then keep doing that. For us it is about taking it for a week and not having to worry about what might have lactose, as well being able to enjoy dairy products in general, without a care.
Also the subscription price is $30 a month, so $1 a day. Convenience holds different value to different people.
Also the subscription price is $30 a month, so $1 a day. Convenience holds different value to different people.
> Different value
OK, I can’t disagree with that ;) I’d say your target is people who are new to figuring out they are lactose intolerant and who are most eager to get a grip on it. I was an early adopter of portable lactase, so I’m set in my ways, but there were plenty of days where I’d forget the pills and it got really frustrating: ordering food that looked great but had to be handed to someone else; unexpected whipped cream frosting on birthday cakes; water and cookies. I still run out sometimes and it’s a drag.
I will make a note to ping you when I’m in Austin. Thanks for that. Would be a fascinating conversation.
OK, I can’t disagree with that ;) I’d say your target is people who are new to figuring out they are lactose intolerant and who are most eager to get a grip on it. I was an early adopter of portable lactase, so I’m set in my ways, but there were plenty of days where I’d forget the pills and it got really frustrating: ordering food that looked great but had to be handed to someone else; unexpected whipped cream frosting on birthday cakes; water and cookies. I still run out sometimes and it’s a drag.
I will make a note to ping you when I’m in Austin. Thanks for that. Would be a fascinating conversation.
The lorem ipsum on the "journal" page does not inspire confidence. But I definitely believe that the idea is feasible. There's that guy who genetically engineered himself to produce lactose[1] and it worked, and this seems like a less risky way to do it. I'd love for a real product along these lines to come out. Would it even be legal to sell it though?
[1] https://www.youtube.com/watch?v=J3FcbFqSoQY
[1] https://www.youtube.com/watch?v=J3FcbFqSoQY
We will be releasing our GMO version in 2022. I anticipate its efficacy to be incredible. We will be performing quite a few safety studies ahead of this release.
The site is brand new, please give it time, my cofounder has remade the site 3 times in the past 7 months, he promises this is the last time though (for now haha).
The site is brand new, please give it time, my cofounder has remade the site 3 times in the past 7 months, he promises this is the last time though (for now haha).
I would suggest a deeper scan of the site for copy editing - there’s at least one mention of “diary” when “dairy” is clearly intended.
(I’d probably wait for more usage and supporting evidence before trying something like this, but the prospect of no-regrets dairy consumption is very appealing.)
(I’d probably wait for more usage and supporting evidence before trying something like this, but the prospect of no-regrets dairy consumption is very appealing.)
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You can find Lactobacillus Acidophilus probiotics at any health food store, or on Amazon. This is hardly novel - and this one appears to be over 23x the price per pill as the existing alternatives! ($1.90/ea vs $0.08/ea)
Yep. They scale the "active ingredient" image down, but here's the larger version: https://cdn.shopify.com/s/files/1/0590/6667/9502/products/bo...
Hi my name is Mike, I am one of the cofounders of Bactories, the creators of Bactose.
Our COGS are $10.09/pack shipped first class mail (add $1.80 if we get the custom shipping box). Then we have to spend on marketing, and spend money on making mistakes, we also have robust R&D activity that needs to be funded. This all adds up, we sell each pack $30 or $40 delivered (as low as $15/pack if use coupons on your first order).
I think our marketing sucks, neither me nor the other founder are good at. If you or if you know someone who can help us with the marketing, to drive down our customer aquisition costs, and increase sales so our COGs decline with increased volumes, I will gladly lower the price. I would rather sell 1 million packs and make $1 on each then sell 1 pack for $1million dollars, if you get what I am saying.
Our COGS are $10.09/pack shipped first class mail (add $1.80 if we get the custom shipping box). Then we have to spend on marketing, and spend money on making mistakes, we also have robust R&D activity that needs to be funded. This all adds up, we sell each pack $30 or $40 delivered (as low as $15/pack if use coupons on your first order).
I think our marketing sucks, neither me nor the other founder are good at. If you or if you know someone who can help us with the marketing, to drive down our customer aquisition costs, and increase sales so our COGs decline with increased volumes, I will gladly lower the price. I would rather sell 1 million packs and make $1 on each then sell 1 pack for $1million dollars, if you get what I am saying.
They claim to have a specific strain which produces lots of lactase, which is possible. I agree with you on principle though.
The supplements market is full of shysters and charlatans. If they had the actual data to prove it, they would have published it.
The only hard data we have currently is when we compared our strain to other LA strains and we were producing about 60% more lactase enzymes. We are in the middle of a double blind clinical study now, that was supposed to finish in October of 2020 (yes 2020), but looks like should hopefully finish in March 2022.
Another piece of data we have is all the anecdotal stuff about it simply working for people, personally I think it is pretty hard to placebo not getting diarrhea.
I do agree with you about the supplement industry being full of scumbags. Let me know what you would like from us to help win you over, besides the double blind which is in progress, but imagine if it was not an option, what else?
Another piece of data we have is all the anecdotal stuff about it simply working for people, personally I think it is pretty hard to placebo not getting diarrhea.
I do agree with you about the supplement industry being full of scumbags. Let me know what you would like from us to help win you over, besides the double blind which is in progress, but imagine if it was not an option, what else?
Since the active ingredient here is 5 billion colony forming units of Lactobacillus acidophilus, I wonder how this differs from getting from another source i.e. yoghurt
> Through our research, we discovered a novel strain of lactobacillus acidophilus bacteria that will colonize the mammalian intestine and actively produce an excess volume of lactase enzymes
It would be nice if there was a paper demonstrating the claims about this specific strain of L. acidophilus
> Through our research, we discovered a novel strain of lactobacillus acidophilus bacteria that will colonize the mammalian intestine and actively produce an excess volume of lactase enzymes
It would be nice if there was a paper demonstrating the claims about this specific strain of L. acidophilus
Hi my name is Mike, I am one of the cofounders of Bactories, the creators of Bactose.
There are only two things truly unique about our strain. 1) It produces about 60% more lactase enzymes than other lactobacillus strains we tested 2) the really key thing, it is evolved to adhere to the mammalian intestinal lining, this is the crucial point of 1 week of taking pills being able to provide 1 or more months of continued efficacy. If you took other LA strains their effects would wear off quickly, why you not get continued lactase tolerance with them.
Let me know any other questions.
There are only two things truly unique about our strain. 1) It produces about 60% more lactase enzymes than other lactobacillus strains we tested 2) the really key thing, it is evolved to adhere to the mammalian intestinal lining, this is the crucial point of 1 week of taking pills being able to provide 1 or more months of continued efficacy. If you took other LA strains their effects would wear off quickly, why you not get continued lactase tolerance with them.
Let me know any other questions.
Have the strains been engineered with a BAC or through CRISPR-type editing or something with Cre-recombinase to get over-expression of lactase?
Any out-patient nutritional studies showing GI intestinal biome data with positive growth conclusions?
Any out-patient nutritional studies showing GI intestinal biome data with positive growth conclusions?
I had diarrhea problems for a few years that no doctor diagnosed. I found on my own that taking a probiotic twice a day completely fixed it, within a few days. The probiotic (Amazon's most popular) was around $13 for 30 pills, so it was going to be $25/mo.
That worked, but instead of spending $25/mo, I started making yogurt and using a couple of opened probiotic capsules as the starter. I'm also recently lactose intolerant, so I let the yogurt ferment 24 hours to ensure all the milk sugar is consumed by the bacteria. I strain it to make Greek yogurt, which to me isn't as tart and tastes more like sour cream. 2 probiotic capsules and a half gallon of milk costs less than $4 for 2 quarts of yogurt. I only have to eat a spoonful in the morning before breakfast. Works great!
If these lactase-producing probiotics actually do work and are safe, making yogurt with them might be an easy and cheap way to get the same benefits.
Edit: corrected the price to $25/mo
That worked, but instead of spending $25/mo, I started making yogurt and using a couple of opened probiotic capsules as the starter. I'm also recently lactose intolerant, so I let the yogurt ferment 24 hours to ensure all the milk sugar is consumed by the bacteria. I strain it to make Greek yogurt, which to me isn't as tart and tastes more like sour cream. 2 probiotic capsules and a half gallon of milk costs less than $4 for 2 quarts of yogurt. I only have to eat a spoonful in the morning before breakfast. Works great!
If these lactase-producing probiotics actually do work and are safe, making yogurt with them might be an easy and cheap way to get the same benefits.
Edit: corrected the price to $25/mo
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284493/