Science absolutely does depend on metaphysics. Most famously: the validity of the scientific method is ultimately a metaphysical extension of our intuitions about inductive reasoning and causality. There is no scientific proof that the scientific method is valid. ("Our intuitions" is why I said metaphysics is tautologically the domain of humans. This is essentially Kant's philosophical legacy: science will describe what it does, but humans intuitively understand reality in ways that defy noncircular scientific description, and metaphysics must be invoked to have a rational and grounded discussion about these intuitions.)