I'm of the opinion that the right time is always now.
However, when things are great, large wealthy companies over-hire and over-pay everyone. It sedates good employees to stay and be comfortable.
When things hit the fan, the larger and fatter a company is, the more likely they will throw the baby out with the bathwater. They go into ultra-stupid cost-cutting mode and that is a great opportunity to hire some of the best dormant employees you'll ever meet.
Since the best determinant of a company's success is the makeup of the team, I'd say when the economy is bad is the best time to start a company. You'll land some of the best talent and that'll give you the best chances of success.
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I think these non-English programming languages are “neat” but ultimately toys unfortunately.