A whole new generation of Mikado is ready to ship and is providing great improvements. One of them is the full support of Server-Side-Rendering (Node.js) and the ability of using hydration. The SSR imeplementation uses the same strategy of shared instances as for the client counterpart. It provdides performance on an extreme level. The SSR also comes with a middleware render engine for Express, which is the fastest you can use today, up to 10x faster than "Marko". Also, both server and client shares the same template markup, making things a lot easier. Mikado is the first library which holds the title for the "best performance benchmarks" on both, client-side and server-side.
One of my favorites is "Whitespace" which could used as a polyglot esoteric language (e.g. to deliver "hidden" code): https://esolangs.org/wiki/Whitespace