Blinkist and skimming a book have their place for getting some of the key points, it's hard to find the time to read all useful books.
But I agree that to really get the most out of a book, reading cover to cover is likely most immersive, impactful, maybe followed by listening to the auduibook from start to finish.
Hypothesis is one that has been interesting to use for web article annotation. It lets you save quotes and comments on articles https://web.hypothes.is/
It's interesting to learn about. Other molecules are also found to inhibit replication of 3CL protease in SARS cov-2 [1].
The UK scientific advisory group SAGE published a few months ago that combination therapy might be useful to avoid 'antiviral resistant' strains of SARS cov-2 evolving. Perhaps these 3cl protease inhibitors may be used in combination.
But I agree that to really get the most out of a book, reading cover to cover is likely most immersive, impactful, maybe followed by listening to the auduibook from start to finish.