In nuclear the saying "there's always enough time to do it right the first time" comes to mind. Preventing rework and reducing risk to the safety of the public.
When it comes to the doe there are likely departments that could be trimmed back and interpretations of some laws to the cfr made a little more clear, but since the doe is in charge of everything nuclear it might be good to do a more indepth look at each department instead of a quick and careless wipe.
Currently nuclear power is regulated in a way of "bring me a rock and I'll tell you if it's the right rock, but if it isn't the right rock it will be painful.