> Figure3 shows plasma levels following a 36g dose of liposomal vitamin C, for both subjects. This resulted in peak plasma levels, in the region of 400mML21. A 95% interfractile range (34–114), which contains 95% of the distribution with a mean of 74 corresponds to a calculated standard deviation of 17.4. We note that, under these conditions, an outlier measurement of 400mML21 would correspond to a deviation of 10.3 s with a theoretical p-value of 1.6610213 (i.e. p,0.0000000000001). With this high dose, both subjects exceeded their bowel tolerance, leading to diarrhoea. This intolerance presumably arose from the high intake of phospholipid, without food buffering, in fasting individuals. However, our observations using hourly doses suggest that daily intakes of this magnitude are tolerable without bowel effects, as long as the dose is spread throughout the day.
https://www.tandfonline.com/doi/abs/10.1080/1359084080230542...
It's interesting that a side effect of pretty much every treatment for cancer is nausea, weight loss, etc. Almost like reduced nutrient absorption is the main mechanism by which the treatments work.
> Regarding quantum states as degrees of belief implies that the event of a quantum state changing when a measurement occurs—the "collapse of the wave function"—is simply the agent updating her beliefs in response to a new experience.
https://en.m.wikipedia.org/wiki/Quantum_Bayesianism
You could be right, That is what this sounds like to me though. According to the model there is a 50% chance the coin will land on heads, until you flip it.
From my reading, they would say some particles are just much more energetic than usual (for some reason we are ignorant of). See the post above about flipping a coin. According to the statistical model we use for coin flips, it is really unlikely to flip 100 heads in a row but not impossible.
Sounds like the wave model describes the statistical properties of a population of photons.
Eg, a coin flip is deterministic if you know all the forces involved (airflow, force of flip, exact distribution of mass of the coin, etc). But since we are usually ignorant of all that, instead we model it as a bernoulli trial.
Cancer cells rely much more on glycolysis than oxidative phosphorylation (respiration, basically breaking down sugar with oxygen). You get a net of two molecules of ATP from glycolysis compared to 30 or so from respiration, so you can expect that cancer cells need much more sugar than normal cells just to survive.
https://en.m.wikipedia.org/wiki/Cellular_respiration
Second, glucose competes with dehydroascorbate (DHA, oxidized vitamin c) for glut1/3 transporters. DHA gets transported into cells (in particular RBC's) to be reduced back to the anti-oxidant form by glutathione: ascorbate. Then that ascorbate molecule can remain in the cell acting as an antioxidant or be pumped back out of the cell to the blood, etc.
If DHA doesn't make it into a cell quickly it gets hydrolyzed and excreted and you lose that molecule of vitamin c. So chronically lower blood sugar is expected to conserve your vitamin c and allow higher ascorbate levels, especially within your cells.
This can have all sorts of beneficial effects. Strengthened collagen makes it easier for a tissue to heal/encapsulate the cancer and harder for it to metastasize, quenching free radicals can prevent damage to surrounding tissue, etc.
Those free radicals can go onto to kill the (high iron) cancer cells. For this reason vitamin C kills almost all cancer cell lines in vitro at doses that do not harm normal cells: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516281/
I met someone who went for a checkup and they convinced him to get a screening colonoscopy. It was clear but a few months later he started having problems and went back. Then they told him he had colon cancer caused by damage to the tissue during the colonoscopy.
> You keep attaching a lot of Pubmed links, but frankly, in this case at least, they aren't all that compelling and don't even begin to approach a scientific consensus.
Which of these statements do you find controversial?
1) Skin cancer rates are rising dramatically
2) Until very recently (in the last ten years) the vast majority of sunblock was transparent to UVA but opaque to UVB
3) Blocking UVB prevents the skins normal darkening and thickening response as well as sunburn
4) UVA penetrates the skin deeper than UVB and causes damage to the DNA in the cells there
5) Damage to the DNA of skin cells is associated with skin cancer
6) Without sunburn to warn people their skin is damaged they are more likely to leave their skin exposed to the sun.
There was no confusion of correlation and causation in my post. It is a clearly stated correlation.
Broad spectrum sunblock may be less than perfect, but until recently all sunblock was transparent to UVA. It blocked UVB which prevented the natural sunburn/tan/thickening response without preventing the DNA damage.
Given the huge growth in skin cancers since people started wearing sunblock it seems likely that it was actively harmful for this reason.
I see, it should have been written "screening-detected" to be as clear as possible.
Yes, the latter is more likely to be comparable over time but it will still have issues with changes in how likely someone is to report it to their doctor, etc.